활용 성과

화합물 활용

활용 성과

약효검색 활용도
  • 연평균 : > 100 산*학*연 과제 지원 (연평균 > 40만종 화합물 반출)
  • 누적 활용 : >800개 과제에 화합물제공 (누적 >650만종 화합물 제공 활용)
국책과제 도출 사례
  • 교과부 중점연구개발과제, 21C 프론티어 사업 과제
  • 후보물질 발굴사업, 연구재단 및 범부처 신약개발사업 등 -> 다수 과제화 

후보물질도출 기여사례

KCB가 제공한 화합물의 활용하여 발견된 유효화합물의 진전연구결과로 도출된 후보물질을 국내외 제약사에 기술이전한 사례를 소개합니다.

활용논문 현황

KCB가 제공한 화합물의 활용결과로 도출된 연구결과를 국내외 전문학술지에 게재된 논문 (KCB에 대한 사사가 포함된 논문)을 소개합니다.

#TitleAuthor(s)JournalYearlinkPublished구분
Discovery and characterization of a potent activator of the BKCa channel that relives overactive bladder syndrome in ratsHeeji Jo, Eun Jung Bae, Narasaem Lee, Jae Won Kwon, Suhan Cho, Sung Joon Kim, Jin Hee Ahn, Chul-Seung Park*European Journal of Pharmacology2022https://doi.org/10.1016/j.ejphar.2022.1750552022.07.15
Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m6A Methylation of RNA in Acute Myeloid Leukemia CellsJe-Heon Lee, Namjeong Choi, Subin Kim, Mi Sun Jin*, Haihong Shen* and Yong-Chul Kim*Pharmaceuticals
2022, 15(4), 440
2022https://doi.org/10.3390/ph150404402022.04.01
3Discovery of harmalanium halides as anti-ovarian cancer agentsYunha Choi, Sang Hee Ji, Vineet Patil, Eun Hye Kim, Hoyeong Park, Seong Hwan Kim*, Pilho Kim*Bulletin of the Korean Chemical Society
2022, 43(4), 559-563
2022https://doi.org/10.1002/bkcs.124982022.02.16
4Celastrol suppresses the growth of vestibular schwannoma in mice by promoting the degradation of β-cateninNa Hui Kim, Minji Kwon, Jiwoo Jung, Hyo Byeong Chae, Jiwoo Lee, Yeo-Jun Yoon, In Seok Moon, Ho K. Lee, Wan Namkung, Konstantina M. Stankovic, Se A. Lee, Jong Dae Lee* & Sin-Aye Park*Acta Pharmacologica Sinica2022https://doi.org/10.1038/s41401-022-00908-42022.04.27
5Discovery and synthesis of 1,2,4-oxadiazole derivatives as novel inhibitors of Zika, dengue, Japanese encephalitis, and classical swine fever virus infectionsSangwoo Nam, Hyo Gyeong Na, Eun Hye Oh, Eunhye Jung, Yeon Hee Lee, Eun Ju Jeong, Yu-Da Ou, Bin Zhou, Sunjoo Ahn, Jin Soo Shin, Soo Bong Han* & Yun Young Go*Archives of Pharmacal Research2022https://doi.org/10.1007/s12272-022-01380-82022.04.20
6Identification and New Indication of Melanin-Concentrating Hormone Receptor 1 (MCHR1) Antagonist Derived from Machine Learning and Transcriptome-Based Drug Repositioning Approaches Gyutae Lim , Ka Young You, Jeong Hyun Lee, Moon Kook Jeon, Byung Ho Lee, Jae Yong Ryu* and Kwang-Seok Oh*International Journal of Molecular Sciences
2022, 23(7), 3807
2022https://doi.org/10.3390/ijms230738072022.03.30
7Discovery of substituted indole derivatives as allosteric inhibitors of m6A-RNA methyltransferase, METTL3-14 complexJe-Heon Lee,Subin Kim,Mi Sun Jin,Yong-Chul Kim*DRUG DEVELOPMENT RESEARCH
online
2022https://doi.org/10.1002/ddr.219102022.01.18
8Synthesis and Structure–Activity Relationship Studies of Benzimidazole-4,7-dione-Based P2X3 Receptor Antagonists as Novel Anti-Nociceptive AgentsJinsu Bae, Yeo-Ok Kim, Xuehao Han, Myung-Ha Yoon, Woong-Mo Kim,* and Yong-Chul Kim*Molecules
2022, 27, 1337
2022https://doi.org/10.3390/molecules270413372022.02.16
9Development of in vitro three-dimensional drug screening system for obesity-related metabolic syndromeKyoung Jin Choi, Joon Ho Lee, Sung Bum Park, Yoon-Ju Na, Won Hoon Jung ,Hyuk Lee*, Ki Young Kim*Journal of Pharmacological Sciences
2022, 148(4),377-386
2022https://doi.org/10.1016/j.jphs.2022.02.0022022.04
10Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer’s disease miceMin Hee Park, Kang Ho Park, Byung Jo Choi, Wan Hui Han, Hee Ji Yoon, Hye Yoon Jung, Jihoon Leed, Im-Sook Song, Dong Yu Lim, Min-Koo Choi* , Yang-Ha Lee, Cheol-Min Park, Ming Wang, Jihoon Jo, Hee-Jin Kim*, Seung Hyun Kim*, Edward H. Schuchman, Hee Kyung Jin and Jae-sung BaePNAS
2022, 119(3), e2115082119
2022https://doi.org/10.1073/pnas.21150821192022.01.13
11Discovery of Mycobacterium tuberculosis Rv3364c-Derived Small Molecules as Potential Therapeutic Agents to Target SNX9 for SepsisDaeun Lee, Eunbi Lee, Sein Jang, Kyungmin Kim, Euni Cho, Seok-Jun Mun, Wooic Son, Hye-In Jeon, Hyo Keun Kim, Young Jin Jeong, Yuno Lee, Ji Eun Oh, Hye Hyun Yoo, Youngbok Lee, Sun-Joon Min,* and Chul-Su Yang*Journal of Medicinal Chemistry,
2022, online
2022https://doi.org/10.1021/acs.jmedchem.1c015512022.01.04
12Discovery and Characterization of a Novel MASTL Inhibitor MKI-2 Targeting MASTL-PP2A in Breast Cancer Cells and OocytesMinsung Kang, Chijung Kim, Jiyeon Leem, Ye-hyun Kim, Young-ju Kwon, Yi Na Yoon, Chong Hak Chae, Jiyeon Ahn, Kwan-Young Jung* , Jeong Su Oh* and Jae-Sung Kim*Pharmaceuticals
2021, 14(7), 647
2021https://doi.org/10.3390/ph14070647
13Chemical Inhibitors of the Conserved Bacterial Transcriptional Regulator DksA1 Suppressed Quorum Sensing-Mediated Virulence of Pseudomonas aeruginosaKyung Bae Min, Wontae Hwang, Kang-Mu Lee, June Beom Kim, Sang Sun Yoon*Journal of Biological Chemistry
2021, 296, 100576
2021https://doi.org/10.1016/j.jbc.2021.100576
5Allosteric Inhibition of the Tumor-Promoting Interaction Between Exon 2–Depleted Splice Variant of Aminoacyl–Transfer RNA Synthetase-Interacting Multifunctional Protein 2 and Heat Shock Protein 70SDae Gyu Kim, Srigouri Huddar, Semi Lim, Jiwon Kong, Yuno Lee, Chul Min Park, Seungbeom Lee, Young-Ger Suh, Minkyoung Kim, Kyeong Lee, Sunkyung Lee and Sunghoon Kim*The Journal of Pharmacology and Experimental Therapeutics
2021, 379(3), 358-371
2021https://doi.org/10.1124/jpet.121.000766
6New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studiesYasmin M. Syam, Manal M. Anwar, Somaia S. Abd El-Karim, Samia A. Elseginy, Basma M. Essa and Tamer M. Sakr RSC Advances
2021,11, 36989-37010
2021https://pubs.rsc.org/en/content/articlelanding/2021/RA/D1RA06799K
7Di (Isoquinolin-1-Yl) Sulfane (DIQS) Inhibits Melaninogenesis by Modulating PKA/CREB and MAPK Signaling PathwaysJung Yoon Yang, Dae-Seop Shin, Kyu-Seok Hwang, Seong Soon Kim, Byung Hoi Lee, Se Hwan Ahn, Jin Hee Ahn and Myung Ae Bae*Cosmetics
2021, 8(4), 104
2021https://doi.org/10.3390/cosmetics8040104
8Aberrant activation of the CD45-Wnt signaling axis promotes stemness and therapy resistance in colorectal cancer cellsSo-Yeon Park, Ji-Young Kim, Gyu-Beom Jang, Jang-Hyun Choi, Jee-Heun Kim, Choong-Jae Lee, Sunjae Lee, Jeong-Heum Baek, Kwan-Kyu Park, Jin-Man Kim, Hee Jin Chang, Nam-Chul Cho, and Jeong-Seok Nam*Theranostics
2021, 11(18), 8755-8770
2021https://www.thno.org/v11p8755.htm
9Development of a FOXM1-DBD Binding Assay for High-Throughput Screening Using TR-FRET AssayMi Young Lee, Chae Eun Haam, Jihye Mun, Gyutae Lim, Byung Ho Lee, and Kwang-Seok Oh*Biological and Pharmaceutical Bulletin
2021, 44(10), 1484–1491
2021https://www.jstage.jst.go.jp/article/bpb/44/10/44_b21-00322/_pdf
10Screening of small molecules attenuating biofilm formation of Acinetobacter baumannii by inhibition of ompA promoter activitySeok Hyeon Na, Hyejin Jeon, Man Hwan Oh, Yoo Jeong Kim & Je Chul Lee*Journal of Microbiology
2021, 59, 871–878
2021https://doi.org/10.1007/s12275-021-1394-z
11Identification of new IL-7Rα small-molecule agonists: a multi-computational approachJ-Y Lee, K Lee, B KohSAR and QSAR in Environmental Research
2021, 32, 719-729
2021https://doi.org/10.1080/1062936X.2021.1969684
12Identification of a novel inhibitor of liver cancer cell invasion and proliferation through regulation of Akt and Twist1Jain Ha, Sewoong Lee, Jiyoung Park, Jihye Seo, Eunjeong Kang, Haelim Yoon, Ba Reum Kim, Hyeon Kyu Lee, Seong Eon Ryu* & Sayeon Cho*Scientific Reports
2021, 11:16765
2021https://doi.org/10.1038/s41598-021-95933-4
13A Novel Frameshifting Inhibitor Having Antiviral Activity against Zoonotic Coronaviruses Dae-Gyun Ahn, Gun Young Yoon, Sunhee Lee, Keun Bon Ku, Chonsaeng Kim, Kyun-Do Kim, Young-Chan Kwon, Geon-Woo Kim, Bum-Tae Kim and Seong-Jun Kim*Viruses
2021, 13(8), 1639
2021https://doi.org/10.3390/v13081639
14Aristolactam BIII, a naturally derived DYRK1A inhibitor, rescues Down syndrome-related phenotypesMiri Choi, Ae-kyeong Kim, Youngwook Ham, Joo-Youn Lee, Daeyong Kim, Ansook Yang, Min Ju Jo, Eunyoung Yoon, Jung-Nyoung Heo, Sang-Bae Han, Min-Hyo Ki, Kyu-Sun Lee, Sungchan Cho*Phytomedicine
2021, 92, 153695
2021https://doi.org/10.1016/j.phymed.2021.153695
15PARIS farnesylation prevents neurodegeneration in models of Parkinson’s diseaseAreum Jo, Yunjong Lee, Tae-In Kam, Sung-Ung Kang, Stewart Neifert, Senthilkumar S. Karuppagounder, Rin Khang, Hojin Kang, Hyejin Park, Shih-Ching Chou, Sungtaek Oh, Haisong Jiang, Deborah A. Swing, Sangwoo Ham, Sheila Pirooznia, George K. E. Umanah, Xiaobo Mao, Manoj Kumar, Han Seok Ko, Ho Chul Kang, Byoung Dae Lee, Yun-Il Lee, Shaida A. Andrabi, Chi-Hu Park, Ji-Yeong Lee, Hanna Kim, Hyein Kim, Hyojung Kim, Jin Whan Cho, Sun Ha Paek, Chan Hyun Na, Lino Tessarollo, Valina L. Dawson, Ted M. Dawson*, Joo-Ho Shin*Science Translational Medicine
2021, 13(604), eaax8891
2021https://stm.sciencemag.org/content/scitransmed/13/604/eaax8891.full.pdf
16Antiviral Activity of Isoquinolone Derivatives against Influenza Viruses and Their Cytotoxicity Yejin Jang, Jinhe Han, Xiaoli Li, Hyunjin Shin, Won-Jea Cho* and Meehyein Kim*Pharmaceuticals
2021, 14(7), 650
2021https://doi.org/10.3390/ph14070650
17Efficient kinetic resolution in the asymmetric transfer hydrogenation of 3-aryl-indanones: applications to a short synthesis of (+)-indatraline and a formal synthesis of (R)-tolterodine†Songsoon Park, Hyeon-Kyu Lee*RSC Advances
2021,11, 23161-23183
2021https://doi.org/10.1039/D1RA04538E
18SARS-CoV-2 aberrantly elevates mitochondrial bioenergetics to induce robust virus propagationHye Jin Shin, Keun Bon Ku, Gun Young Yun, Hyun-Woo Moon, Chonsaeng Kim, Bum-Tae Kim, Jong-Won Oh, Aleem Siddiqui, and Seong-Jun Kim,*Research Square
2021, online
2021https://doi.org/10.21203/rs.3.rs-593889/v1
19Structure-Based Virtual Screening: Identification of a Novel NS2B-NS3 Protease Inhibitor with Potent Antiviral Activity against Zika and Dengue Viruses Hye Jin Shin, Mi-Hwa Kim, Joo-Youn Lee, Insu Hwang, Gun Young Yoon, Hae Soo Kim, Young-Chan Kwon, Dae-Gyun Ahn, Kyun-Do Kim, Bum-Tae Kim, Seong-Jun Kim*, Chonsaeng Kim*Microorganisms
2021, 9(3), 545
2021https://doi.org/10.3390/microorganisms9030545
20Novel FoxO1 inhibitor, JY-2, ameliorates palmitic acid-induced lipotoxicity and gluconeogenesis in a murine modelHye-Eun Choi, YuSik Kim, Han-Joo Lee, Hyae Gyeong Cheon*European Journal of Pharmacology
2021, 899, 174011
2021https://doi.org/10.1016/j.ejphar.2021.174011
21A new KSRP-binding compound suppresses distant metastasis of colorectal cancer by targeting the oncogenic KITENIN complexJeong A Bae, Woo Kyun Bae, Sung Jin Kim, Yoo-Seung Ko, Keon Young Kim, So-Yeon Park, Young Hyun Yu, Eun Ae Kim, Ik Joo Chung, Hangun Kim, Hyung-Ho Ha & Kyung Keun KimMolecular Cancer
2021, 20, 78
2021https://doi.org/10.1186/s12943-021-01368-w
22Anti-Cancer Effects of Glaucarubinone in the Hepatocellular Carcinoma Cell Line Huh7 via Regulation of the Epithelial-To-Mesenchymal Transition-Associated Transcription Factor Twist1 Jihye Seo, Jain Ha, Eunjeong Kang, Haelim Yoon, Sewoong Lee, Shi Yong Ryu, Kwonseop Kim and Sayeon Cho* International Journal of Molecular Sciences
2021, 22(4), 1700
2021https://doi.org/10.3390/ijms22041700
23Discovery of μ,δ-Opioid Receptor Dual-Biased Agonists That Overcome the Limitation of Prior Biased AgonistsJin Hee Lee, Suh-Youn Shon, Woojin Jeon, Sung-Jun Hong, Junsu Ban, and Do Sup Lee*ACS Pharmacology & Translational Science
2021, online
2021https://doi.org/10.1021/acsptsci.1c00044
24Sildenafil prevents HDACi-induced Epstein-Barr virus reactivation through the PKG pathway in NK/T cell lymphoma; potential implications for HDACi-mediated fatal complicationsJoo Hyun Kim, Won Seog Kim*, Chaehwa Park*Antiviral Research
2021, 189, 105063
2021https://doi.org/10.1016/j.antiviral.2021.105063
25Identification of non-covalent 3C-like protease inhibitors against severe acute respiratory syndrome coronavirus-2 via virtual screening of a Korean compound libraryJoo-Youn Lee, Chih-Jung Kuo, Jin Soo Shin, Eunhye Jung, Po-Huang Liang*, and Young-Sik Jung*Bioorganic & Medicinal Chemistry Letters
2021, 42, 128067
2021https://doi.org/10.1016/j.bmcl.2021.128067
26Design, synthesis and biological evaluation of 2-aminoquinazolin-4(3H)-one derivatives as potential SARS-CoV-2 and MERS-CoV treatmentsJun Young Lee, Young Sup Shin, Sangeun Jeon, Se In Lee, Soojin Noh, Jung-Eun Cho, Min Seong Jang, Seungtaek Kim, Jong Hwan Song, Hyoung Rae Kim, Chul Min Park*Bioorganic & Medicinal Chemistry Letters
2021, 39, 127885
2021https://doi.org/10.1016/j.bmcl.2021.127885
27Antimicrobial activity of IDD-B40 against drug-resistant Mycobacterium tuberculosisMd Imtiazul Islam, Hoonhee Seo, Sukyung Kim, Venkata S. Sadu, Kee-In Lee & Ho-Yeon SongScientific Reports
2021,11,740
2021https://www.nature.com/articles/s41598-020-80227-y
28Radicicol Inhibits Chikungunya Virus Replication by Targeting Nonstructural Protein-2Sangwoo Nam, Yun Ji Ga, Joo-Youn Lee, Woo-Yeon Hwang, Eunhye Jung, Jinsoo Shin, Weiyi Chen, Gildon Choi, Bin Zhou, Jung-Yong Yeh, Yun Young Go*Antimicrobial Agents and Chemotherapy
2021, 65(7), e00135-21
2021https://doi.org/10.1128/AAC.00135-21
29Application of the antitussive agents oxelaidin and butamirate as anti-glioma agentsSook-Ja Lee, Seon-Yong Yeom, Jee-Young Lee & Chaehwa Park*Scientific Reports
2021, 11:10145
2021https://doi.org/10.1038/s41598-021-89238-9
30Novel brd4 inhibitors with a unique scaffold exhibit antitumor effectsYoung Hun Kim, Minsung Kim, Ji Eun Kim, Miyoun Yoo, Heung Kyoung Lee, Chong Ock Lee, Minjin Yoo, Kwan-Young Jung, Yeongrin Kim, Sang Un Choi, Chi Hoon Park*Oncology Letters
2021, 21(6), 473
2021https://doi.org/10.3892/ol.2021.12734
31TIMP-1-expressing breast tumor spheroids for the evaluation of drug penetration and efficacyIn Yeong Bae, Wooshik Choi, Seung Ja Oh, Chansoo Kim, Sang-Heon Kim*Bioengineering & Translational Medicine
2021, e10286
2021https://doi.org/10.1002/btm2.10286
32A microwave-assisted synthetic approach to analyzing disubstituted pyrrolo[2,3-d]pyrimidine diversity via ligand-free Cu-catalyzed N-arylationChang Sung Hong, Seung Yeong Park, Jeong Seob Byeon, Eul Kgun Yum*Bulletin of the Korean Chemical Society
2021, 42(12), 1641-1649
2021https://doi.org/10.1002/bkcs.12422
33Therapeutic Effects of Inhibitor of ompA Expression against Carbapenem-Resistant Acinetobacter baumannii StrainsSeok-Hyeon Na, Hyejin Jeon, Man-Hwan Oh, Yoo-Jeong Kim, Mingi Chu, Ill-Young Lee and Je-Chul Lee*International Journal of Molecular Sciences
2021, 22(22), 12257
2021https://doi.org/10.3390/ijms222212257
34In Silico Exploration of Conformational Dynamics and Novel Inhibitors for Targeting MEF2-Associated Transcriptional ActivityAyisha Zia Orcid, Muhammad Imran and Sajid Rashid*Journal of Chemical Information and Modeling2020, 60, 1892−19092020https://doi.org/10.1021/acs.jcim.0c00008
35Development and structure-activity relationship study of SHP2 inhibitor containing3,4,6-trihydroxy-5-oxo-5H-benzo[7]annuleneBohee Kim, Seungjin Jo, Sung Bum Park, Chong Hak Chae, Kwangho Lee, Byumseok Koh*, Inji Shin*Bioorganic & Medicinal Chemistry Letters2020, 30(1), 1267562020https://doi.org/10.1016/j.bmcl.2019.126756
36Rifamycin O, An Alternative Anti-Mycobacterium abscessus AgentBui Thi Bich Hanh, June-Woo Park, Tae Ho Kim, Jae-Sung Kim, Chul-Su Yang, Kiseok Jang, Jinsheng Cui, Dong-Chan Oh and Jichan Jang*Molecules2020, 25(7), 15972020https://doi.org/10.3390/molecules25071597
37Discovery of a Novel Chemical Scaffold Against Mutant Isocitrate Dehydrogenase 1 (IDH1)Chung Hyo Kang, Sang Un Choi, You Hwa Son, Heung Kyoung Lee, Hye Gwang Jeong , Chang-Soo Yun, Sunjoo Ahn, Chi Hoon ParkAnticancer Research2020http://ar.iiarjournals.org/content/40/9/4929
38Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2Dae Gyu Kim, Chul Min Park, Srigouri Huddar, Semi Lim, Sunghoon Kim*, Sunkyung Lee*Molecules2020, in press2020https://chembank.org/%ed%99%9c%ec%9a%a9%eb%85%bc%eb%ac%b8/
39Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activityDong-Gyun Kim, Sujin Cho, Kyu-Yeon Lee, Seung-Ho Cheon, Hye-Jin Yoon, Joo-Youn Lee, Dongyoon Kim, Kwang-Soo Shin, Choong-Hyun Koh, Ji Sung Koo, Yuri Choi, Hyung Ho Lee, Yu-Kyoung Oh, Yoo-Seong Jeong, Suk-Jae Chung, Moonkyu Baek, Kwan-Young Jung, Hyo Jin Lim, Hyoun Sook Kim, Sung Jean Park, Jeong-Yeon Lee, Sang Jae Lee* & Bong-Jin Lee*Cellular and Molecular Life Sciences, 2021, 78(1), 207-2252020https://doi.org/10.1007/s00018-020-03490-2
40Peripheral Inhibition of Small C‐Terminal Domain Phosphatase 1 With Napthoquinone AnalogsHarikrishna Reddy Rallabandi, Dongsun Lee, Jinmo Sung, YoungJun KimBulletin of the Korean Chemical Society2020, in press2020https://doi.org/10.1002/bkcs.12051
41Autophagic inhibition via lysosomal integrity dysfunction leads to antitumor activity in glioma treatmentHui-Yun Hwang, Yoon Sun Cho, Jin Young Kim, Ki Na Yun, Jong Shin Yoo, Eunhyeong Lee, Injune Kim and Ho Jeong Kwon*Cancers2020, 12(3), 5432020https://doi.org/10.3390/cancers12030543
42TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activationHyun-Kyoung Kim, Kashi Raj Bhattarai, Raghu Patil Junjappa, Jin Hee Ahn, Suvarna H. Pagire, Hyun Ju Yoo, Jaeseok Han, Duckgue Lee, Kyung-Woon Kim, Hyung-Ryong Kim *, Han-Jung Chae*Nature Communications2020https://www.nature.com/articles/s41467-020-17802-4
43Identification of a New Chemotype of Anti-Obesity Compounds by Ensemble ScreeningHyunkyung Cho, Joo-Youn Lee, Sang Yoon Choi, Chaemin Lim, Min-Kyoung Park, Hyejin An, Jeong Ok Lee, Minsoo Noh, Seunghee Lee* and Sanghee Kim*ACS Omega2020, 5, 8, 4338-43462020https://doi.org/10.1021/acsomega.9b04454
44Role of RS-1 derivatives in homology-directed repair at the human genome ATG5 locusIn-Sook Jeon, Jae-Cheon Shin, Seung Ryul Kim, Kwan Sik Park, Hyun Jung Yoo, Kwang Youl Lee, Hak-Kyo Lee, Joong-Kook ChoiArchives of Pharmacal Research2020, in press2020https://link.springer.com/article/10.1007/s12272-020-01226-1
45DeepHIT: a deep learning framework for prediction of hERG-induced cardiotoxicityJae Yong Ryu*, Mi Young Lee, Jeong Hyun Lee, Byung Ho Lee and Kwang-Seok Oh*Bioinformatics2020, 36(10), 3049–30552020https://doi.org/10.1093/bioinformatics/btaa075
46L-type Calcium Channel Blocker Enhances Cellular Delivery and Gene Silencing Potency of Cell-Penetrating Asymmetric siRNAsJeong Yong Choe, Da Seul Son, Yanghee Kim, Jun-kyoung Lee, Hanho Shin, Won Jun Kim, Young Gyu Kang, Pooja Dua, Sun Woo Hong, June Hyun Park and Dong-ki Lee*Molecular Pharmaceutics2020, 17, 3, 777-7862020https://doi.org/10.1021/acs.molpharmaceut.9b00942
47Identification of Diphenoxylate as an Antiviral Agent Against Severe Acute Respiratory Syndrome Coronavirus 2Jin Soo Shin Eunhye Jung Yejin Jang Soo Bong Han Meehyein Kim*ChemRxivs2020, in press2020https://doi.org/10.26434/chemrxiv.12496547.v1
48In silico screening of GABA aminotransferase inhibitors from the constituents of Valeriana officinalis by molecular docking and molecular dynamics simulation studyJin-Young Park, Yuno Lee, Hee Jae Lee, Yong-Soo Kwon, Wanjoo Chun*Journal of Molecular Modeling2020https://link.springer.com/article/10.1007/s00894-020-04495-1#Sec9
49Inhibitory effects on Streptococcus mutans of antibacterial agents mixed withexperimental fluoride varnishJu-Lee SON, Ah-Jin KIM, Seunghan OH, Ji-Myung BAEDental Materials Journal2020, in press2020https://doi.org/10.4012/dmj.2020-016
50Identification of 4-Anilino-6-aminoquinazoline Derivatives as Potential MERS-CoV InhibitorsJun Young Lee, Young Sup Shin, Jihye Lee, Sunoh Kwon, Young-hee Jin, Min Seong Jang, Seungtaek Kim, Jong Hwan Song, Hyoung Rae Kim, Chul Min Park*Bioorganic & Medicinal Chemistry Letters2020https://www.sciencedirect.com/science/article/pii/S0960894X20305837
51Efficacy and pharmacokinetics evaluation of 4-(2-chloro-4-fluorobenzyl)-3-(2-thienyl)-1,2,4-oxadiazol-5(4H)-one (GM-90432) as an anti-seizure agentKyu-Seok Hwang, Hyemin Kan, Seong Soon Kim, Jin Sil Chae, Jung Yoon Yang, Dae-Seop Shin, Se Hwan Ahn, Jin Hee Ahn, Jin-Hwa Cho, Il-Sung Jang, Junnyeong Shin, Jaeyoung Joo, Cheol-Hee Kim, Myung Ae Bae*Neurochemistry International2020https://doi.org/10.1016/j.neuint.2020.104870
52Chemical Inhibitors of DksA1, a Conserved Bacterial Transcriptional Regulator, Suppressed Quorum Sensing-Mediated Virulence in Pseudomonas aeruginosaKyung Bae Min, Wontae Hwang, Kang-Mu Lee, Sang Sun YoonbioRxiv2020https://doi.org/10.1101/2020.12.10.420422
53A novel tyrosine kinase inhibitor can augment radioactive iodine uptake through endogenous sodium/iodide symporter (NIS) expression in anaplastic thyroid cancerMs. Ji Min Oh, Mr. Se Hwan Baek, Dr. Prakash Gangadaran, Dr. Chae Moon Hong, Dr. Ramya Lakshmi Rajendran, Dr. Ho Won Lee, Mr. Liya Zhu, Mr. Arunnehru gopal, Dr. Senthilkumar Kalimuthu, Prof. Shin Young Jeong, Dr. Sang-Woo Lee, Dr. Jaetae Lee, and Dr. Byeong-Cheol Ahn*Thyroid2020, 30(4), 501-5182020https://doi.org/10.1089/thy.2018.0626
54Selection and functional identification of a synthetic partial ABA agonist, S7Myung Ki Min, Rigyeong Kim, Seok-Jun Moon, Yongsang Lee, Seungsu Han, Sangho Lee & Beom-Gi Kim*Scientific Reports2020, 10(4)2020https://doi.org/10.1038/s41598-019-56343-9
55A computational drug repurposing approach in identifying the cephalosporin antibiotic and anti-hepatitis C drug derivatives for COVID-19 treatmentRaj Kumar, Vikas Kumar, Keun Woo LeeComputers in Biology and Medicine2020https://doi.org/10.1016/j.compbiomed.2020.104186
56Application of multi-omics technology for the elucidation of anti-pneumococcal activity of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one (APDQ) derivative against Streptococcus pneumoniaeSang‑Yeop Lee, Hayoung Lee, Sung Ho Yun, Sangmi Jun, Yujeong Lee, Wooyoung Kim, Edmond Changkyun Park, Joonyoung Baek, Yoonna Kwak, Soojin Noh, Giwan Seo, Soojin Jang, Chul Min Park* & Seung Il Kim*Scientific Reports2020https://doi.org/10.1038/s41598-020-77694-8
57Identification of new arylsulfide derivatives as anti-melanogenic agents in a zebrafish modelSe Hwan Ahn, Kyu-Seok Hwang, Dae-Seop Shin, Seong Soon Kim, Jung Yoon Yang, Byung Hoi Lee, Eun Jung Bae, Byeong Wook Choi, Myung Ae Bae, Jin Hee AhnBioorganic & Medicinal Chemistry Letters2020, 30(13), 1272012020https://doi.org/10.1016/j.bmcl.2020.127201
58Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcRSeung Min Kim, Jongmin Park, Myun Soo Kim, Heebum Song, Ala Jo, Hankum Park, Tae Sung Kim, Sang Ho Choi,* and Seung Bum ParkACS Infectious Diseases2020https://doi.org/10.1021/acsinfecdis.0c00587
59Discovery of 4-hydroxy-2-oxo-1,2-dihydroquinolines as potential inhibitors of Streptococcus pneumoniae, including drug-resistant strainsSrigouri Huddar, Chul Min Park, Hyung Jun Kim, Soojin Jang, Sunkyung LeeBioorganic & Medicinal Chemistry Letters2020, 30(9), 1270712020https://doi.org/10.1016/j.bmcl.2020.127071
60Diversification of Heteroaryl‐Aryl Ether via Ligand‐Free, Copper‐Catalyzed O‐Arylation Under Microwave Heating Sung Min Choi, Jeong Seob Byeon, Eul Kgun Yum*Bulletin of the Korean Chemical Society2020https://onlinelibrary.wiley.com/doi/full/10.1002/bkcs.12075
61Structural and Functional Study of the Klebsiella pneumoniae VapBC Toxin–Antitoxin System, Including the Development of an Inhibitor That Activates VapCSung-Min Kang, Chenglong Jin, Do-Hee Kim, Yuno Lee, Bong-Jin Lee*Journal of Medicinal Chemistry2020https://doi.org/10.1021/acs.jmedchem.0c01118
62Antiviral activity of sertindole, raloxifene and ibutamoren against transcription and replication-competent Ebola virus-like particlesYi-Seul Yoon, Yejin Jang, Thomas Hoenen, Heegwon Shin, Younghoon Lee & Meehyein Kim*BMB Reports2020, 53(3), 166-1712020https://doi.org/10.5483/BMBRep.2020.53.3.175
63Punicalagin Ameliorates Lupus Nephritis via Inhibition of PAR2Yohan Seo, Chin Hee Mun, So-Hyeon Park, Dongkyu Jeon, Su Jeong Kim, Taejun Yoon, Eunhee Ko, Sungwoo Jo, Yong-Beom Park, Wan Namkung, and Sang-Won LeeInternational Journal of Molecular Sciences2020https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404282/
64Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2Young Sup Shin, Jun Young Lee, Soojin Noh, Yoonna Kwak, Sangeun Jeon, Sunoh Kwon, Young-hee Jin, Min Seong Jang, Seungtaek Kim, Jong Hwan Song, Hyoung Rae Kim, Chul Min Park*Bioorganic & Medicinal Chemistry Letters2020https://doi.org/10.1016/j.bmcl.2020.127667
65Phenylethylamides derived from bacterial secondary metabolites specifically inhibit an insect serotonin receptorAriful Hasan, Hyun-Suk Yeom, Jaewook Ryu, Helge B. Bode & Yonggyun KimScientific Reports20358 (2019)2019https://doi.org/10.1038/s41598-019-56892-z
66Discovery of (E)-5,5-Difluoro-1-[2-[5-(3-fluorophenyl)pyridin-2-yl]vinyl]octahydrospiro(indene-2,5′-oxazolidin)-2′-one as a PAR1 Antagonist Chul Min Park, Sunkyung Lee, Song Jong Hwan, Lee Joo YounBulletin of the Korean Chemical Society2019, 40, 658-6672019https://doi.org/10.1002/bkcs.11747
67Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic DiseasesDahye Lee, Haushabhau S. Pagire, Suvarna H. Pagire, Eun Jung Bae, Mahesh Dighe, Minhee Kim, Kyu Myung Lee, Yoon Kyung Jang, Ashok Kumar Jaladi, Kwan-Young Jung, Eun Kyung Yoo, Hee Eon Gim, Seungmi Lee, Won-Il Choi, Young-In Chi, Jin Sook Song, Myung Ae Bae, Yong Hyun Jeon, Ga-Hyun Lee, Kwang-Hyeon Liu, Taeho Lee, Sungmi Park, Jae-Han Jeon, In-Kyu Lee, and Jin Hee AhnJournal of Medicinal Chemistry2019, 62(2), 575-5882019https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01168
68Identification of a novel turn-on albumin binding small-molecule bioprobe in live zebrafish and its potential application in drug discoveryHang-Suk Chun,Seo-Jung Han,Dae-Seop Shin,Haushabhau S.Pagire,Suvarna H.Pagire,Gwi Bin Lee,Chong Hak Chae,BoryeongPak,Suk-Won Jin,Young-Tae Chang,Seung Bum Park,Jin Hee Ahn,Myung Ae BaeDyes and Pigments2019, 171, 1077202019https://doi.org/10.1016/j.dyepig.2019.107720
69Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish modelJeong Kun-HeeKim,Dong-Young Kim,GopalakrishnanChandrasekaran,Minhee Kim,Suvarna H.Pagire,Mahesh Dighe,Eun Young Choi,Su-Min Bak,Eun-Young Kim,Myung-Geun Shin,Seok-Yong Choi,Jin Hee AhnBioorganic & Medicinal Chemistry2019, 27(19), 1150142019https://doi.org/10.1016/j.bmc.2019.07.030
70A Small Molecule Targeting Mutagenic Translesion Synthesis Improves ChemotherapyJessica L. Wojtaszek, Nimrat Chatterjee, Javaria Najeeb, Azucena Ramos, Minhee Lee, Ke Bian, Jenny Y. Xue, Benjamin A. Fenton, Hyeri Park, Deyu Li, Michael T. Hemann, Jiyong Hong, Graham C. Walker, and Pei ZhouCell2019, 178(1), 152-1592019https://doi.org/10.1016/j.cell.2019.05.028
71Synthesis and biological evaluation of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4(1H)-one derivatives as potential MERS-CoV inhibitorsJi HyeYoon,Jun Young Lee,Jihye Lee,Young Sup Shin,Sangeun Jeon,Dong Eon Kim,Jung Sun Min,Jong Hwan Song,Seungtaek Kim,Sunoh Kwon,Young-hee Jin,Min Seong Jang,Hyoung Rae Kim,Chul Min ParkBioorganic & Medicinal Chemistry LettersVolume 29, Issue 23, 1 December 2019, 1267272019https://doi.org/10.1016/j.bmcl.2019.126727
72Identification of a novel SIRT7 inhibitor as anticancer drug candidateJi-Hye Kim, Da hee Kim, Suk Joon Cho, Kwan-Young Jung, Jong-Hoon Kim, Jun Mi Lee, Hee Jung Jung, Kwang Rok KimBiochemical and Biophysical Research Communications2019, 508(2), 451-4572019https://doi.org/10.1016/j.bbrc.2018.11.120
73The anti-biofilm and anti-virulence activities of trans-resveratrol and oxyresveratrol against uropathogenic Escherichia coliJin-Hyung Lee,Yong-Guy Kim,Chaitany Jayprakash Raorane,Shi Yong Ryu,Jae-Jin Shim &Jintae LeeThe Journal of Bioadhesion and Biofilm Research2019, 35(7) 758-7672019https://doi.org/10.1080/08927014.2019.1657418
74DITMD-induced mitotic defects and apoptosis in tumor cells by blocking the polo-box domain-dependent functions of polo-like kinase 1Ka-Ul Kim, Ju Hee Lee, Mi Young Lee, Chong Hak Chae, Jeong Hyun Lee, Byung Ho Lee, Kwang-Seok OhEuropean Journal of Pharmacology2019, 847, 113-1222019https://doi.org/10.1016/j.ejphar.2019.01.032
75In vitro activity of DNF-3 against drug resistant Mycobacterium tuberculosisMd Imtiazu Islam, Choi Moon Han, Hoonhee Seo, Sukyung Kim, Hafij Al Mahmud, Kung-Woo Nam, Byung-Eui Lee, Venkata S. Sadu, Kee-In Lee, Ho-Yeon SongInternational Journal of Antimicrobial Agents2019, 54(1), 69-742019https://doi.org/10.1016/j.ijantimicag.2019.02.013
76Potential biomarkers and antagonists for fluoranthene-induced cellular toxicity of bone marrow derived mesenchymal stem cellsMd Moinul Hoque,Young Eun Lee, Hye Ran Kim,and Myung Geun ShinSynapse2019 Dec;54(4):253-2612019https://doi.org/10.5045/br.2019.54.4.253
77Homoharringtonine Induces Apoptosis in Human Colorectal Carcinoma HCT116 Cells Via Downregulation of Wnt/β-Catenin Signaling CascadeMikyung Park, Hojeong Kwon, and Seong Hwan KimBulletin of the Korean Chemical Society2019, 40(2), 196-1992019https://onlinelibrary.wiley.com/doi/epdf/10.1002/bkcs.11662
78A nano sensor for sensitive and selective detection of Cu2+ based on fluorescein: Cell imaging and drinking water analysisPrasad G.Mahajan, Nilam C.Dige, Balasaheb D.Vanjare, Seong-Hui Eo, Song Ja Kim, Ki Hwan LeeSpectrochimica Acta Part A : Molecular and Biomolecular Spectroscopy2019, 216, 105-1162019https://onlinelibrary.wiley.com/doi/epdf/10.1002/bkcs.11662
79Facile synthesis of new quinazolinone benzamides as potent tyrosinase inhibitors: Comparative spectroscopic and molecular docking studiesPrasad G.Mahajan,Nilam C.Dige,Balasaheb D.Vanjare,Hussain Raza,Mubashir Hassan,Sung-Yum Seo,Chong- Hyeak Kim,Ki Hwan LeeJournal of Molecular StructureVolume 1198, 15 December 2019, 1269152019https://doi.org/10.1016/j.molstruc.2019.126915
80Stereoselective Synthesis of Highly Functionalized 5- and 6-Membered Aminocyclitols Starting with a Readily Available 2-AzetidinoneRaghavendra Achary, Hyeong Rae Kim, Hyeon-Kyu LeeThe Journal of Organic Chemistry2019, 84(7), 4263-42722019https://pubs.acs.org/doi/pdf/10.1021/acs.joc.9b00239
81Synthesis and Biological Evaluation of PF-543 Derivative Containing Aliphatic Side ChainSeon Woong Kim, Taeho Lee, Yoon Sin Oh, Sang Mi Shin, Joo-Youn Lee, Sanghee Kim, Dong Jae Baek, and Eun-Young ParkChemical and Pharmaceutical Bulletin2019, 67(6), 599-6032019https://www.jstage.jst.go.jp/article/cpb/67/6/67_c18-00724/_pdf
82Fluoranthene-Induced Cytotoxicity and Direct Effect of Aryl Hydrocarbon Receptor Antagonist on Hematopoietic Stem Cell DifferentiationSeung-Hyun Yang,Min-Gu Kang,Hye-Ran Kim,Young Eun Lee,Bo Ram Na,Jun Hyung Lee,Jong-Hee Shin,and Myung-Geun ShinAnn Lab Med2019 Nov;39(6):580-5832019https://doi.org/10.3343/alm.2019.39.6.580
83Thiostrepton: A Novel Therapeutic Drug Candidate for Mycobacterium abscessus InfectionTae Ho Kim,Bui Thi Bich Hanh,Guehye Kim,Da-Gyum Lee,June-Woo Park,So Eui Lee,Jae-Sung Kim,Byoung Soo Kim,Sungweon Ryoo,Eun-Kyeong Jo,andJichan JangMolecules2019, 24(24), 45112019https://doi.org/10.3390/molecules24244511
84Discovery of Small‐Molecule Modulators of Protein–RNA Interactions by Fluorescence Intensity‐Based Binding AssayWan Gi Byun Dr. Donghyun Lim Prof. Dr. Seung Bum ParkChemBioChem2019,20,1–82019https://doi.org/10.1002/cbic.201900467
85Small-molecule inhibitor of HlyU attenuates virulence of Vibrio speciesZee-Won Lee, Byoung Sik Kim, Kyung Ku Jang, Ye-Ji Bang, Suhyeon Kim, Nam-Chul Ha, Young Hyun Jung, Hyun Jik Lee, Ho Jae Han, Jong-Seo Kim, Jeesoo Kim, Pramod K. Sahu, Lak Shin Jeong, Myung Hee Kim & Sang Ho ChoiScientific Reports2019, 9, 436-4492019https://www.nature.com/articles/s41598-019-39554-y
86Anti-inflammatory effects of a novel compound, MPQP, through the inhibition of IRAK1 signaling pathways in LPS-stimulated RAW 264.7 macrophagesBa Reum Kim, Young-Chang Cho & Sayeon ChoBMB Reports2018, 51(6), 308-3132018https://doi.org/10.5483/BMBRep.2018.51.6.064
87Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activityBonsu Ku, Hye-Yeoung Yun, Kyung WonLee, Ho-Chul Shin, Sang-Rae Lee, Chang Hyen Kim, Hwangseo Park, Kyu Yang Yi, Chang Hoon Lee, Seung Jun KimBioorganic & Medicinal Chemistry Letters2018, 26(18), 5204-52112018https://doi.org/10.1016/j.bmc.2018.09.022
88QStatin, a Selective Inhibitor of Quorum Sensing in Vibrio SpeciesByoung Sik Kim, Song Yee Jang, Ye-ji Bang, Jungwon Hwang, Youngwon Koo, Kyung Ku Jang, Dongyeol Lim, Myung Hee Kim, Sang Ho ChoimBio2018, 9(1), e02262-172018http://dx.doi.org/10.1128/mBio.02262-17
89Design and Synthesis of Novel 3-(2-Aminopyridin-3-yl)-1,2,4-Triazolo[4,3-b]Pyridazine Derivatives as a Reversible Bruton’s Tyrosine Kinase InhibitorsChi Hoon Park, Dukwoon Kim, Hyeonseok Jung, Jeong Hee Jeon, Raghavendra Achary, Joo-Youn Lee, Pilho Kim, Heejung Jung, Jong Yeon Hwang, Do Hyun Ryu, Jae Du Ha, and Sung Yun ChoBulletin of the Korean Chemical Society2018, 온라인 게재2018http://dx.doi.org/10.1002/bkcs.11485
90Restoring Let-7 microRNA Biogenesis Using a Small-Molecule Inhibitor of the Protein-RNA InteractionDonghyun Lim, Wan Gi Byun, and Seung Bum ParkACS Medicinal Chemistry Letters2018, 9(12), 1181-11852018https://doi.org/10.1021/acsmedchemlett.8b00323
91Identification and Characterization of NTB451 as a Potential Inhibitor of NecroptosisEun-Jung In, Yuno Lee, Sushruta Koppula, Tae-Yeon Kim, Jun-Hyuk Han, Kwang-Ho Lee, and Tae-Bong KangMolecules2018, 23(11), 2884-28992018https://doi.org/10.3390/molecules23112884
92Identification of quinone analogues as potential inhibitors of picornavirus 3C protease in vitroEunhye Jung, Joo-Youn Lee, Ho Jeong Kim, Chung-Kyu Ryu, Kee-In Lee, Meehyein Kim, Chong-Kyo Lee, Yun Young GoBioorganic & Medicinal Chemistry Letters2018, in press2018https://doi.org/10.1016/j.bmcl.2018.05.046
93A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetesHyejin Lim, Yu-Mi Lim, Kook Hwan Kim, Young Eui Jeon, Kihyoun Park, Jinyoung Kim, Hui-Yun Hwang, Dong Jin Lee, Haushabhau Pagire, Ho Jeong Kwon, Jin Hee Ahn & Myung-Shik LeeNATURE COMMUNICATIONS2018, 9, 14382018http://dx.doi.org/10.1038/s41467-018-03939-w
94DBU-Promoted Dynamic Kinetic Resolution in Rh-Catalyzed Asymmetric Transfer Hydrogenation of 5-Alkyl Cyclic Sulfamidate Imines: Stereoselective Synthesis of Functionalized 1,2-Amino AlcoholsHyeong Rae Kim, Raghavendra Achary, and Hyeon-Kyu LeeJournal of Organic Chemistry2018, 83(19), 11987-119992018https://doi.org/10.1021/acs.joc.8b01892
95Reverting iodine avidity of radioactive-iodine refractory thyroid cancer with a new tyrosine kinase inhibitor (K905-0266) excavated by high-throughput NIS (sodium iodide symporter) enhancer screening platform using dual reporter gene systemJi Min Oh, Senthilkumar Kalimuthu, Prakash Gangadaran, Se Hwan Baek, Liya Zhu, Ho Won Lee, Ramya Lakshmi Rajendran, Chae Moon Hong, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee and Byeong-Cheol AhnOncotarget2018, 9(6), 7075-70872018http://dx.doi.org/10.18632/oncotarget.24159
96Fluvastatin activates sirtuin 6 to regulate sterol regulatory element-binding proteins and AMP-activated protein kinase in HepG2 cellsJi-Hye Kim, Jun Mi Lee, Jong-Hoon Kim, Kwang Rok KimBiochemical and Biophysical Research Communications2018, 503(3), 1415-14212018https://doi.org/10.1016/j.bbrc.2018.07.057
97Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In VitroJin Soo Shin, Eunhye Jung, Meehyein Kim, Ralph S. Baric and Yun Young GoViruses2018, 10, 2832018http://dx.doi.org/10.3390/v10060283
98Synthesis of Novel FTY720 Analogs with Anticancer Activity through PP2A ActivationJitendra Shrestha, Sung Hwan Ki, Sang Mi Shin, Seon Woong Kim, Joo-Youn Lee, Hee-Sook Jun, Taeho Lee, Sanghee Kim, Dong Jae Baek and Eun-Young ParkMolecules2018, 23(11), 2750-27612018https://doi.org/10.3390/molecules23112750
99Suppression of NRF2/ARE by convallatoxin sensitises A549 cells to 5-FU-mediated apoptosisJune Lee, Jong-Su Kang, Le Ba Nam, Ok-Kyung Yoo, and Young-Sam KeumFree Radical Research2018, 온라인 게재2018https://doi.org/10.1080/10715762.2018.1489132
100A pivotal role of AMPK signaling in medicarpin-mediated formation of Brown and BeigeKhan Mohammad Imran, Dahyeon Yoon, Yong-Sik KimBioFactors2018, 44(2), 168-1792018http://dx.doi.org/10.1002/biof.1392
101A novel anti-melanogenic agent, KDZ-001, inhibits tyrosinase enzymatic activityKyu-Seok Hwang, Jung Yoon Yang, Jooyun Lee, Yu-Ri Lee, Seong Soon Kim, Geum Ran Kim, Jin Sil Chae, Jin Hee Ahn, Dae-Seop Shin, Tae-Young Choi, Myung Ae BaeJournal of Dermatological Science2018, 89, 165-1712018http://dx.doi.org/10.1128/mBio.02262-17
102Synthesis and biological evaluation of indazole-4,7-dione derivatives as novel BRD4 inhibitorsMinjin Yoo, Miyoun Yoo, Ji Eun Kim, Heung Kyoung Lee, Chong Ock Lee, Chi Hoon Park, Kwan-Young JungArchives of Pharmacal Research2018, 41(1), 46-562018http://dx.doi.org/10.1007/s12272-017-0978-y
103Effects of a small molecule R-spondin-1 substitute RS-246204 on a mouse intestinal organoid cultureMyeong-Ok Nam, Soojung Hahn, Joo Hyun Jee, Tae-Sun Hwang, Ho Yoon, Dong Hyeon Lee, Min-Soo Kwon and Jongman YooOncotarget2018, 9(5), 6356-63682018http://dx.doi.org/10.18632/oncotarget.23721
104Tandem Rh-Catalyzed Oxidative C?H Olefination and Cyclization of Enantiomerically Enriched Benzo-1,3-Sulfamidates: Stereoselective Synthesis of trans-1,3-Disubstituted IsoindolinesRaghavendra Achary, In-A Jung, and Hyeon-Kyu LeeJournal of Organic Chemistry2018, 83(7), 3864-38782018http://dx.doi.org/10.1021/acs.joc.8b00204
105Psoralidin Stimulates Expression of Immediate-Early Genes and Synapse Development in Primary Cortical NeuronsSeojin Hwang, Seong-eun Lee, Sang-Gun Ahn, Gum Hwa LeeNeurochemical Research2018, 43(2), 2460-24722018https://link.springer.com/content/pdf/10.1007/s11064-018-2689-2.pdf
106Mosquitocidal activity of penfluridol as juvenile hormone antagonistSeok-Hee Lee, Hee Nam Lim, Jae Young Choi, Dong Hwan Park, Byung Hoon Ahn, Ying Fang, Jong Hoon Kim, Min Gu Park, Ra Mi Woo, Bo Ram Lee, Woo Jin Kim, Young Kwan Ko, Ill Young Lee, Yeon Ho JeJournal of Asia-Pacific Entomology2018, 21, 130-1332018https://doi.org/10.1016/j.aspen.2017.11.009
107Synthesis and Biological Evaluation of FTY720 (Fingolimod) Derivatives with Aromatic Head Group as Anticancer AgentsTaeho Lee, Hong Seop Moon, Seon Woong Kim, Jitendra Shrestha, Sang Mi Shin, Joo-Youn Lee, Sanghee Kim, Eun-Young Park, and Dong Jae BaekChemical and Pharmaceutical Bulletin2018, 66(10), 1015-10182018https://doi.org/10.1248/cpb.c18-00065
108Salinomycin Inhibits Influenza Virus Infection by Disrupting Endosomal Acidification and Viral Matrix Protein 2 FunctionYejin Jang, Jin Soo Shin, Yi-Seul Yoon, Yun Young Go, Hye Won Lee, Oh Seung Kwon, Sehee Park, Man-Seong Park, Meehyein KimJournal of Virology2018, 92(24), e01441-182018https://doi.org/10.1128/JVI.01441-18
109A natural compound, aristoyagonine, is identified as a potent bromodomain inhibitor by mid-throughput screeningYoung Hun Kim, Minsung Kim, Miyoun Yoo, Ji Eun Kim, Heung Kyoung Lee, Jung-Nyoung Heo, Chong Ock Lee, Minjin Yoo, Kwan-Young Jung, Chang-Soo Yun, Sung Woong Moon, Hye Kyung Chang, Chul-Woong Chung, Suhkneung Pyo, Sang Un Choi, Chi Hoon ParkBiochemical and Biophysical Research Communications2018, 503, 882-8872018https://doi.org/10.1016/j.bbrc.2018.06.091
110실험용 항균성 불소바니쉬의 최소억제농도와 최소살균농도손주리, 김아진, 오승한, 배지명Korean Journal of Dental Materials2018, 45(2), 139-1462018http://dx.doi.org/10.14815/kjdm.2018.45.2.139
111Enterovirus inhibitory activity of C-8-tert-butyl substituted 4-aryl-6,7,8,9-tetrahydrobenzo[4,5]thieno[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(4H)-onesBishyajit Kumar Biswas, Yashwardhan R. Malpani, Neul Ha, Do-Hyun Kwon, Jin Soo Shin, Hae-Soo Kim, Chonsaeng Kim, Soo Bong Han, Chong-Kyo Lee, Young-Sik JungBioorganic & Medicinal Chemistry Letters2017, 27, 3582-35852017http://dx.doi.org/10.1016/j.bmcl.2017.05.030
1123-Amino-1H-pyrazolopyridine Derivatives as a Maternal Embryonic Leucine Zipper Kinase InhibitorChul Min Park, Vithal B. Jadhav, Jong-Hwan Song, Sunkyung Lee, Hee Young Won, Sang Un Choi, and You Hwa SonBulletin of the Korean Chemical Society2017, 38(6), 595-6022017http://dx.doi.org/10.1002/bkcs.11129
113KRICT-9 inhibits neuroinflammation, amyloidogenesis and memory loss in Alzheimer’s disease modelsDo Yeon Lee, Chul Ju Hwang, Ji Yeon Choi, Mi Hee Park, Min Ji Song, Ki Wan Oh, Sang Bae Han, Woo Kyu Park, Hee Yeong Cho, Sung Yun Cho, Hye Byn Park, Min Jong Song and Jin Tae HongOncotarget2017, 8(40), 68654-686672017http://dx.doi.org/10.18632/oncotarget.19818
114Synthesis and Molecular Modeling Studies of N'-Hydroxyindazolecarboximidamides as Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) InhibitorsDong-Ho Lee, Joo-Youn Lee, Jieun Jeong, Miok Kim, Kyung Won Lee, Eunseo Jang, Sunjoo Ahn, Chang Hoon Lee and Jong Yeon HwangMolecules2017, 22, 1936-19452017https://doi.org/10.3390/molecules22111936
115A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancerE-J Choi, B-J Jung, S-H Lee, H-S Yoo, E-A Shin, H-J Ko, S Chang, S-Y Kim and S-M JeonOncogene2017, 36, 5285-52952017http://dx.doi.org/10.1038/onc.2017.153
116Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding InhibitorsEun-Jin Han, Hyun Young Kim, Naeun Lee, Nam-Hoon Kim, Seung-Ah Yoo, H. Moo Kwon, Dae-Myung Jue, Yune-Jung Park, Chul-Soo Cho, Tran Quang De, Dae Young Jeong, Hee-Jong Lim, Woo Kyu Park, Ge Hyeong Lee, Heeyeong Cho, Wan-Uk KimEBioMedicine2017, 18, 261-2732017http://dx.doi.org/10.1016/j.ebiom.2017.03.039
117Replacing the terminal piperidine in ceritinib with aliphatic amines confers activities against crizotinib-resistant mutants including G1202RGangadhar Rao Mathi, Chung Hyo Kang, Heung Kyoung Lee, Raghavendra Achary, Ha-Yeon Lee, Joo-Youn Lee, Jae Du Ha, Sunjoo Ahn, Chi Hoon Park, Chong Ock Lee, Jong Yeon Hwang, Chang-Soo Yun, Hee Jung Jung, Sung Yun Cho, Hyoung Rae Kim, Pilho KimEuropean Journal of Medicinal Chemistry2017, 126, 536-5492017http://dx.doi.org/10.1016/j.ejmech.2016.11.046
118The Discovery of Novel Protein Tyrosine Phosphatase ε Inhibitors Using a High-throughput Screening ApproachHye-Yeoung Yun, Bonsu Ku, Hye Seon Lee, Ho-Chul Shin, Jun-Beom Park, Chang Hyen Kim, and Seung Jun KimBulletin of the Korean Chemical Society2017, 38, 44-532017http://dx.doi.org/10.1002/bkcs.11044
119Design and Synthesis of Novel Pyrazolo[3,4-d]pyrimidin-1-yl piperidine Derivatives as Bruton's Tyrosine Kinase InhibitorsHyebin Park, Chi Hoon Park, Seung-Tae Kang, Jeong Hee Jeon, Raghavendra Archary, Joo-Youn Lee, Pilho Kim, Heejung Jung, Chang-Soo Yun, Jong Yeon Hwang, Do Hyun Ryu, and Sung Yun ChoBulletin of the Korean Chemical Society2017, 38, 278-2812017http://dx.doi.org/10.1002/bkcs.11065
120An Efficient Copper-catalyzed Nucleophilic Addition to N-Acyliminium Ions Derived from N-Benzyloxycarbonylamino Sulfones: A Novel Approach to C-3 Functionalization of 2-Phenylimidazo[1,2-a]pyridineHyeong Jin Park and Jong-Gab JunBulletin of the Korean Chemical Society2017, 38, 1123-11282017http://dx.doi.org/10.1002/bkcs.11228
121Identification of Antipneumococcal Molecules Effective Against Different Streptococcus pneumoniae Serotypes Using a Resazurin-Based High-Throughput ScreenHyung Jun Kim, Namyoul Kim, David Shum, Srigouri Huddar, Chul Min Park, and Soojin JangASSAY and Drug Development Technologies2017, 15(5), 198-2092017http://dx.doi.org/10.1089/adt.2017.789
122BET Inhibitors as Anticancer Agents : A Patent ReviewImran Ali, Gildon Choi and Kwangho LeeRecent Patents on Anti-Cancer Drug Discovery2017, 12, 340-3642017https://doi.org/10.2174/1574892812666170808121228
123Discovery of novel [1,2,4]triazolo[4,3-a]quinoxaline aminophenyl derivatives as BET inhibitors for cancer treatmentImran Ali, Jooyun Lee, Areum Go, Gildon Choi, Kwangho LeeBioorganic & Medicinal Chemistry Letters2017, 27, 4606-46132017http://dx.doi.org/10.1016/j.bmcl.2017.09.025
124A Novel Series of Highly Potent Small Molecule Inhibitors of Rhinovirus ReplicationJinwoo Kim, Yu Kyoung Jung, Chonsaeng Kim, Jin Soo Shin, Els Scheers, Joo-Youn Lee, Soo Bong Han, Chong-Kyo Lee, Johan Neyts, Jae-Du Ha, and Young-Sik JungJournal of Medicinal Chemistry2017, 60, 5472-54922017http://dx.doi.org/10.1021/acs.jmedchem.7b00175
125Identification of novel ALK2 inhibitors and their effect on cancer cellsMinsung Kim, Okran Choi, Suhkneung Pyo, Sang Un Choi, Chi Hoon ParkBiochemical and Biophysical Research Communications2017, 492, 121-1272017http://dx.doi.org/10.1016/j.bbrc.2017.08.016
126Antihelminthic drug niclosamide inhibits CIP2A and reactivates tumor suppressor protein phosphatase 2A in non-small cell lung cancer cellsMyeong-ok Kim, Min Ho Choe, Yi Na Yoon, Jiyeon Ahn, Minjin Yoo, Kwan-Young Jung, Sungkwan An, Sang-Gu Hwang, Jeong Su Oh, Jae-Sung KimBiochemical Pharmacology2017, 144(15), 78-892017http://dx.doi.org/10.1016/j.bcp.2017.08.009
127Synthesis of Fluorescent Indazoles by Palladium-Catalyzed Benzannulation of Pyrazoles with AlkynesOg Soon Kim, Jin Hyeok Jang, Hyun Tae Kim, Su Jin Han, Gavin Chit Tsui, and Jung Min JooOrganic Letters2017, 19(6), 1450-14532017http://dx.doi.org/10.1021/acs.orglett.7b00410
128Stereoselective Synthesis of Functionalized 1, 3-Disubstituted Isoindolines via Rh(III)-Catalyzed Tandem Oxidative Olefination-Cyclization of 4-Aryl-cyclic Sulfamidate-5-CarboxylatesRaghavendra Achary, In-A Jung, Se-Mi Son, and Hyeon-Kyu LeeThe Journal of Organic Chemistry2017, 82, 7223-72332017http://dx.doi.org/10.1021/acs.joc.7b00799
129Antimicrobial activity of novel 4H-4-oxoquinolizine compounds against extensively drug-resistant Acinetobacter baumannii strainsSeok Hyeon Na, Hyejin Jeon, Yoo Jeong Kim, Hyo Il Kwon, Gati Noble Selasi, Asiimwe Nicholas, Chang-Soo Yun, Sang Ho Lee, Je Chul LeeInternational Journal of Antimicrobial Agents2017, 49, 107-1112017http://dx.doi.org/10.1016/j.ijantimicag.2016.10.008
130Development of an HTS system to identify natural chemicals that specifically inhibit Escherichia coli O157:H7 adhesion to host cellsSeung Min Kim, Hyun Jung KimFood Control2017, 73, 185-1922017http://dx.doi.org/10.1016/j.foodcont.2016.08.007
131Activity of novel inhibitors of Staphylococcus aureus biofilmsSeung-Gyun Woo, So-Yeon Lee, So-Min Lee, Kyoung-Hee Lim, Eun-Ju Ha, Yong-Bin EomFolia Microbiologica2017, 62(2), 157-1672017http://dx.doi.org/10.1007/s12223-016-0485-4
132Acceleration of osteoblast differentiation by a novel osteogenic compound, DMP-PYT, through activation of both the BMP and Wnt pathwaysSu Jung Bae, Hye Joo Kim, Hee Yeon Won, Yong Ki Min and Eun Sook HwangScientific Reports2017, 7, 8455-84642017http://dx.doi.org/10.1038/s41598-017-08190-9
133Synthesis and biological evaluation of N9-cis-cyclobutylpurine derivatives for use as cyclin-dependent kinase (CDK) inhibitorsSun Jun Park, Eunjin Kim, Miyoun Yoo, Joo-Youn Lee, Chi Hoon Park, Jong Yeon Hwang, Jae Du HaBioorganic & Medicinal Chemistry Letters2017, 27(18), 4399-44042017http://dx.doi.org/10.1016/j.bmcl.2017.08.018
134Development of a High-Throughput Assay for Inhibitors of the Polo-Box Domain of Polo-Like Kinase 1 Based on Time-Resolved Fluorescence Energy TransferTae Gi Kim, Ju Hee Lee, Mi Young Lee, Ka-Ul Kim, Jeong Hyun Lee, Chi Hoon Park, Byung Ho Lee, and Kwang-Seok OhBiological and Pharmaceutical Bulletin2017, 40(9), 1454-14622017http://doi.org/10.1248/bpb.b17-00283
135Anti-cancer effect of novel PAK1 inhibitor via induction of PUMAmediated cell death and p21-mediated cell cycle arrestTae-Gyun Woo, Min-Ho Yoon, Shin-Deok Hong, Jiyun Choi, Nam-Chul Ha, Hokeun Sun, Bum-Joon ParkOncotarget2017, 8(14), 23690-237012017http://dx.doi.org/10.18632/oncotarget.15783
136Naphthofuroquinone derivatives show strong antimycobacterial activities against drug-resistant MycobacteriaWoong Sik Jang, Young-Sang Choi, Sukyung Kim, Md. Anirban Jyoti, Hoonhee Seo, Juhye Han, Yong-Sik Kim, Jiwon Lyu, Kung-Woo Nam, Byung-Eui Lee, Kee-In Lee & Ho-Yeon SongJournal of Chemotherapy2017, 29(6), 338-3432017http://dx.doi.org/10.1080/1120009X.2017.1296987
137On-Chip Peptide Mass Spectrometry Imaging for Protein Kinase Inhibitor ScreeningYoung-Lai Cho, Young-Pil Kim, Jin Gyeong Son, Miyoung Son, and Tae Geol LeeAnalytical Chemistry2017, 89, 799-8062017http://dx.doi.org/10.1021/acs.analchem.6b03557
138Inhibiting DX2-p14/ARF Interaction Exerts Antitumor Effects in Lung Cancer and Delays Tumor ProgressionAh-Young Oh, Youn Sang Jung, Jiseon Kim, Jee-Hyun Lee, Jung-Hyun Cho, Ho-Young Chun, Soyoung Park, Hyunchul Park, Sikeun Lim, Nam-Chul Ha, Jong Sook Park, Choon-Sik Park, Gyu-Yong Song, and Bum-Joon ParkCancer Research2016, 76(16), 4791-48042016http://dx.doi.org/10.1158/0008-5472.CAN-15-1025
139Dihydroergotamine Tartrate Induces Lung Cancer Cell Death through Apoptosis and MitophagyChang S.-H., Lee A.Y., Yu K.-N., Park J., Kim K.P., Cho M.-H.Chemotherapy2016, 61(6), 304-3122016http://dx.doi.org/10.1159/000445044
140Minor modifications to ceritinib enhance anti-tumor activity in EML4-ALK positive cancerChung Hyo Kang, Eun-Young Kim, Hyoung Rae Kim, Chong Ock Lee, Heung Kyoung Lee, Hye Gwang Jeong, Sang Un Choi, Chang-Soo Yun, Jong Yeon Hwang, Joo-Youn Lee, You Hwa Son, Sunjoo Ahn, Byung Hoi Lee, Heejung Jung, Chi Hoon ParkCancer Letters2016, 374, 272-2782016http://dx.doi.org/10.1016/j.canlet.2016.02.009
141Novel 2,4-diaminopyrimidines bearing tetrahydronaphthalenyl moiety against anaplastic lymphoma kinase (ALK): Synthesis, in vitro, ex vivo, and in vivo efficacy studiesDawn Song, Minji Lee, Chi Hoon Park, Sunjoo Ahn, Chang Soo Yun, Chong Ock Lee, Hyoung Rae Kim, Jong Yeon HwangBioorganic & Medicinal Chemistry Letters2016, 26, 1720-17252016http://dx.doi.org/10.1016/j.bmcl.2016.02.052
142DDRI-9: a novel DNA damage response inhibitor that blocks mitotic progressionDong Wha Jun, Mihwa Hwang, Yun-Hee Kim, Kyung-Tae Kim, Sunshin Kim and Chang-Hun LeeOncotarget20162016http://dx.doi.org/10.18632/oncotarget.7135
143Small molecules that allosterically inhibit p21-activated kinase activity by binding to the regulatory p21-binding domainDuk-Joong Kim, Chang-Ki Choi, Chan-Soo Lee, Mee-Hee Park, Xizhe Tian, Nam Doo Kim, Kee-In Lee, Joong-Kwon Choi, Jin Hee Ahn, Eun-Young Shin, Injae Shin and Eung-Gook KimExperimental & Molecular Medicine2016, 48, e2292016http://dx.doi.org/10.1038/emm.2016.13
144A Dual Readout Assay Based on Fluorescence Polarization and Time-Resolved Fluorescence Resonance Energy Transfer to Screen for RSK1 InhibitorsEun-mi Jeong, Mi Young Lee, Jeong Hyun Lee, Byung Ho Lee, Kwang-Seok OhBiological and Pharmaceutical Bulletin (Japan)2016, 39, 547-5552016http://dx.doi.org/10.1248/bpb.b15-00808
145Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extensionHye Seon Lee, Bonsu Ku, Tae Hyun Park, Hwangseo Park, Joong-Kwon Choi, Kyu-Tae Chang, Cheol-Hee Kim, Seong Eon Ryu, Seung Jun KimBioorganic & Medicinal Chemistry Letters2016, 26(1), 87-932016http://www.sciencedirect.com/science/article/pii/S0960894X15302341
146Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapyHyun-Yi Kim, Sehee Choi, Ji-Hye Yoon, Hwan Jung Lim, Hyuk Lee, Jiwon Choi, Eun Ji Ro, Jung-Nyoung Heo, Weontae Lee, Kyoung Tai No & Kang-Yell ChoiEMBO Molecular Medicine20162016http://dx.doi.org/10.15252/emmm.201505714
147Development of potent chemical antituberculosis agents targeting Mycobacterium tuberculosis acetohydroxyacid synthaseIn-Pil Jung, Na-Reum Ha, Sang-Choon Lee, Sung-Weon Ryoo, Moon-Young YoonInternational Journal of Antimicrobial Agents2016, 48, 247-2582016http://dx.doi.org/10.1016/j.ijantimicag.2016.04.031
148Calcium-chelating alizarin and other anthraquinones inhibit biofilm formation and the hemolytic activity of Staphylococcus aureusJin-Hyung Lee, Yong-Guy Kim, Shi Yong Ryu, Jintae LeeScientific Reports2016, 1, 8642016http://dx.doi.org/10.1038/srep19267
149IinQ attenuates systemic inflammatory responses via selectively impairing the Myddosome complex formation upon TLR4 ligationKidong Kang†, Minho Won†, Jae-Min Yuk†, Chan-Yong Park, Hee Sun Byun, Kyeong Ah Park, So-Ra Lee, Young-Goo Kang, Han-Ming Shen, Ill Young Lee, Gang Min HurBiochemical Pharmacology2016, 121, 52-662016http://dx.doi.org/10.1016/j.bcp.2016.09.017
150Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking studyMinju Kim, Sunhoe Lee, Eun Beul Park, Kwang Jong Kim, Hwi Ho Lee, Ji-Sun Shin, Katrin Fischer, Andreas Koeberle, Oliver Werz, Kyung-Tae Lee, Jae Yeol LeeBioorganic & Medicinal Chemistry Letters2016, 26(1), 94-992016http://www.sciencedirect.com/science/article/pii/S0960894X1530233X
151Chromo/Fluorogenic Detection of Co2+, Hg2+ and Cu2+ by the Simple Schiff Base SensorMuhammad Saleem, Chung Ho Khang, Moon-Hwan Kim, Ki Hwan LeeJournal of Fluorescence - RAPID COMMUNICATION2016, 26(1), 11-222016http://link.springer.com/article/10.1007/s10895-015-1723-x
152Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screeningMyoung Eun Jung, Byung Jin Byun, Hye-Mi Kim, Joo Yun Lee, Jin-Hee Park, Nari Lee, You Hwa Son, Sang Un Choi, Kyung-Min Yang, Seong-Jin Kim, Kwangho Lee, Yong-Chul Kim, Gildon ChoiBioorganic & Medicinal Chemistry Letters2016, 26(11), 2719-27232016http://dx.doi.org/10.1016/j.bmcl.2016.03.111
153Stereoselective synthesis of 1,3-disubstituted isoindolines via Rh(III)-catalyzed tandem oxidative olefination-cyclization of 4-aryl cyclic sulfamidatesSe-Mi Son, Yeon Ji Seo, and Hyeon-Kyu LeeChemComm2016, 52, 4286-42892016http://dx.doi.org/10.1039/c5cc09888b
154Activity of novel inhibitors of Staphylococcus aureus biofilmsSeung-Gyun Woo, So-Yeon Lee, So-Min Lee, Kyoung-Hee Lim, Eun-Ju Ha, Yong-Bin EomFolia Microbiologica2016, 61, 1-112016http://dx.doi.org/10.1007/s12223-016-0485-4
155Urinary Bladder-Relaxant Effect of Kurarinone Depending on Potentiation of Large-Conductance Ca2+-Activated K+ ChannelsSojung Lee, Mee Ree Chae, Byoung-Cheol Lee, Yong-Chul Kim, Jae Sue Choi, Sung Won Lee, Jae Hoon Cheong, and Chul-Seung ParkMolecular Pharmacology2016, in press2016http://dx.doi.org/10.1124/mol.115.102939
156Interruption of progerin.lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotypeSu-Jin Lee, Youn-Sang Jung, Min-Ho Yoon, So-mi Kang, Ah-Young Oh, Jee-Hyun Lee, So-Young Jun, Tae-Gyun Woo, Ho-Young Chun, Sang Kyum Kim, Kyu Jin Chung, Ho-Young Lee, Kyeong Lee, Guanghai Jin, Min-Kyun Na, Nam Chul Ha, Clea Barcena, Jose M.P. Freije, Carlos Lopez-Otin, Gyu Yong Song and Bum-Joon ParkJournal of Clinical Investigation2016, 126(10), 3879-38932016http://dx.doi.org/10.1172/JCI84164
157Novel 3-amino-7-(aminomethyl)-1H-indazol-4-ol as the PI3Kγ enzyme inhibitorSukumar Bepary, In Kwon Yoon, and Ge Hyeong LeeBulletin of the Korean Chemical Society2016, 37, 2054-20572016http://dx.doi.org/10.1002/bkcs.10994
158Peptide inhibition of p22phox and Rubicon interaction as a therapeutic strategy for septic shockYe-Ram Kim, Hyun-Jung Koh, Jae-Sung Kim, Jin-Seung Yun, Kiseok Jang, Joo-Youn Lee, Jae U. Jung, Chul-Su YangBiomaterials2016, 101, 47-592016http://dx.doi.org/10.1016/j.biomaterials.2016.05.046
159Diacetoxyscirpenol as a new anticancer agent to target hypoxiainducible factor 1Yong-Joon Choi, Hyun-Woo Shin, Yang-Sook Chun, Alain Simplice Leutou, Byeng Wha Son, Jong-Wan ParkOncotarget2016, 7(38), 62107-621222016http://dx.doi.org/10.18632/oncotarget.11529
160Identification of Mitotic Blockers by Phenotypic Screening of a Clinical Compound LibraryYou Hwa Son, Chi Hoon Park, and Sang Un ChoiBulletin of the Korean Chemical Society2016, 37, 1942-19462016http://dx.doi.org/10.1002/bkcs.10999
161Identification of a New Morpholine Scaffold as a P2Y12 Receptor AntagonistYoung Ha Ahn†, Joo-Youn Lee†, Hee Dong Park, Tae Hun Kim, Min Chul Park, Gildon Choi and Sunghoon KimMolecules2016, 21, 1114-11242016http://dx.doi.org/10.3390/molecules21091114
162Secreted tryptophanyl-tRNA synthetase as a primary defence system against infectionYoung Ha Ahn†, Sunyoung Park†, Jeong June Choi, Bo-Kyung Park, Kyung Hee Rhee, Eunjoo Kang, Soyeon Ahn, Chul-Ho Lee, Jong Soo Lee, Kyung-Soo Inn, Mi-La Cho, Sung-Hwan Park, Kyunghee Park, Hae Jung Park, Jae Hyun Lee, Jung Won Park, Nam Hoon Kwon, Hyunbo Shim, ByungWoo Han, Pilhan Kim, Joo-Youn Lee, Youngho Jeon, Jin Won Huh, Mirim Jin and Sunghoon KimNature Microbiology2016, 2, 1-122016http://dx.doi.org/10.1038/NMICROBIOL.2016.191
163Selective and Efficient Elimination of Vibrio cholerae with a Chemical Modulator that Targets Glucose MetabolismYoung Taek Oh, Hwa Young Kim, Eun Jin Kim, Junhyeok Go, Wontae Hwang, Hyoung Rae Kim, Dong Wook Kim and Sang Sun YoonFrontiers in Cellular and Infection Microbiology2016, 6, 1562016http://dx.doi.org/10.3389/fcimb.2016.00156
164Synthesis and evaluation of novel 2,4-diaminopyrimidines bearing bicyclic aminobenzazepines for anaplastic lymphoma kinase (ALK) inhibitorGa Ae Kang, Minji Lee, Dawn Song, Heung Kyoung Lee, Sunjoo Ahn, Chi Hoon Park, Chong Ock Lee, Chang Soo Yun, Heejung Jung, Pilho Kim, Jae Du Ha, Sung Yun Cho, Hyoung Rae Kim, Jong Yeon HwangBioorganic & Medicinal Chemistry Letters2015, 25(18), 3992-39982015http://www.sciencedirect.com/science/article/pii/S0960894X15007088
165Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptorHyeon Young Kim, Vithal B. Jadhav, Dae Young Jeong, Woo Kyu Park, Jong-Hwan Song, Sunkyung Lee, Heeyeong ChoArchives of Pharmacal Research2015, 38, 1019-10322015http://link.springer.com/article/10.1007/s12272-015-0560-4
166Praeruptorin A Inhibits in Vitro Migration of Preosteoclasts and in Vivo Bone Erosion, Possibly Due to Its Potential To Target CalmodulinJeong-Tae Yeon, Sik-Won Choi, Byung Jun Ryu, Kwang-Jin Kim, Joo Yun Lee, Byung Jin Byun, Young-Jin Son and Seong Hwan KimJournal of Natural Products2015, 78, 776-7822015http://pubs.acs.org/doi/abs/10.1021/np501017z
167A lipophilic fluorescent LipidGreen1-based quantification method for high-throughput screening analysis of intracellular poly-3-hydroxybutyrateJi Eun Choi, Hye Young Na, Taek Ho Yang, Sung-Keun Rhee and Jae Kwang SongAMB Express2015, 5, 482015, 5, 482015http://www.amb-express.com/content/5/1/48
168An indoxyl compound 5-bromo-4-chloro-3-indolyl 1,3-diacetate, CAC-0982, suppresses activation of Fyn kinase in mast cells and IgE-mediated allergic responses in miceJun Ho Lee, Tae Hyung Kim, Hyuk Soon Kim, A-Ram Kim, Do-Kyun kim, Seung Taek Nam, HyunWoo Kim, Young Hwan Park, Erk Her, Yeong Min Park, Hyung Sik Kim, Young Mi Kim, Wahn Soo ChoiToxicology and Applied Pharmacology2015, 285(3), 179-1862015http://www.sciencedirect.com/science/article/pii/S0041008X15001398
169Synthesis of 4-(3,4-dicarboxamido-1H-pyrrole)pyrimidines as Anaplastic Lymphoma Kinase InhibitorsMuhammad Latif, Byung Jin Byun and Kwangho LeeBulletin of the Korean Chemical Society2015, 36(2), 520-5252015https://onlinelibrary.wiley.com/doi/full/10.1002/bkcs.10097
170Design, Synthesis, and Evaluation of 2-Anilino-4-(3,5-dicarbox- amidespiperidine)-pyrimidines as Anaplastic Lymphoma Kinase InhibitorsMuhammad Latif, Sangjun Park, Imran Ali, Hyeonjeong Choe, Chong Hak Chae, Chi Hoon Park, Hyoung Rae Kim, Chang-Soo Yun and Kwangho LeeBulletin of the Korean Chemical Society2015, 36(2), 2397-24002015http://onlinelibrary.wiley.com/doi/10.1002/bkcs.10454/abstract;jsessionid=6E868AC9024F2D91A18E2354099C25F1.f03t04
171Quinoline Compound KM11073 Enhances BMP-2-Dependent Osteogenic Differentiation of C2C12 Cells via Activation of p38 Signaling and Exhibits In Vivo Bone Forming ActivitySeung-hwa Baek, Sik-Won Choi, Sang-Joon Park, Sang-Han Lee, Hang-Suk Chun, Seong Hwan KimPLOS ONE2015, 10(3): e01201502015http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120150
172Identification of a novel 11β-HSD1 inhibitor from a high-throughput screen of natural product extractsSung Bum Park, Ji Seon Park, Won Hoon Jung, AReum Park, Sae Rom Jo, Hee Youn Kim, Sang Dal Rhee, Shi Yong Ryu, Hye Gwang Jeong, Seongsoon Park, Hyuk Lee, Ki Young KimPharmacological Research2015, 102, 245-2532015http://www.sciencedirect.com/science/article/pii/S1043661815002571
173Stereoselective Synthesis of 4-Substituted Cyclic Sulfamidate-5-Phosphonates by Using Rh-Catalyzed, Asymmetric Transfer Hydrogenation with Accompanying Dynamic Kinetic ResolutionYeon Ji Seo, Jin-ah Kim, and Hyeon-Kyu LeeThe Journal of Organic Chemistry2015, 80(17), 8887-89022015http://pubs.acs.org/doi/10.1021/acs.joc.5b01434
174Synthesis and anti-tubercular activity of 2-nitroimidazooxazines with modification at the C-7 position as PA-824 analogsYoung-Goo Kang, Chan-Yong Park, Hongsuk Shin, Ramandeep Singh, Garima Arora, Chan-mo Yu, Ill Young LeeBioorganic & Medicinal Chemistry Letters2015, 25(17), 3650-36532015http://www.sciencedirect.com/science/article/pii/S0960894X15006538
175Discovery and the structural basis of a novel p21-activated kinase 4 inhibitorByung Jun Ryu, Sunmin Kim, Bora Min, Keon Young Kim, Jin Soo Lee, Whui Jung Park, Hyuk Lee, Seong Hwan Kim, Sang Youn ParkCancer Letters2014, 349(1), 45-502014https://doi.org/10.1016/j.canlet.2014.03.024
1764-Substituted quinazoline derivatives as novel EphA2 receptor tyrosine kinase inhibitorsChae Jo Lim, Kwang-Seok Oh, Jae Du Ha, Jeong Hyun Lee, Ho Won Seo, Chong Hack Chae, Dae-Ghon Kim, Mi-Jin Lee, Byung Ho LeeBioorganic & Medicinal Chemistry Letters2014, 24, 4080-40832014https://doi.org/10.1016/j.bmcl.2014.07.081
177Identification of a series of 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) pyridin-2-amines, as a new class of G-protein-coupled receptor kinase 2 and 5 inhibitorCheon Ho Park, Mi Young Lee, Jeong Hyun Lee, Byung Ho Lee, Kwang-seok OhReceptors & Clinical Investigation2014, 1(4), 112-1142014http://dx.doi.org/10.1172/JCI200524178
178Inhibition of STAT3 activation by KT-18618 via the disruption of the interaction between JAK3 and STAT3Dae-Seop Shin, Seung Nam Jung, Jieun Yun, Chang Woo Lee, Dong Cho Han, BumTae Kim, Yong Ki Min, Nam Sook Kang, Byoung-Mog KwonBiochemical Pharmacology2014, 89(1), 62-732014https://doi.org/10.1016/j.bcp.2014.02.017
1796-Trifluoromethyl-2-thiouracil possesses anti-Toxoplasma gondii effect in vitro and in vivo with low hepatotoxicityHwa-Jung Choi, Seung-Taek Yu, Kee-In Lee, Joong-Kwon Choi, Bo-Yoon Chang, Sung-Yeon Kim, Mi-Hwa Ko, Hyun-Ok Song, Hyun ParkExperimental Parasitology2014, 143, 24-292014https://doi.org/10.1016/j.exppara.2014.05.002
180ALK inhibitors of bis-ortho-alkoxy-para-piperazinesubstituted-pyrimidines and -triazines for cancer treatmentHyeon Ji Lee, Muhammad Latif, Hyeonjeong Choe, Imran Ali, Heung Kyoung Lee, Eun Hye Yang, Jeong In Yun, Chong Hak Chae, Jae-Kyung Jung, Hyoung Rae Kim, Chong Ock Lee, Chi Hoon Park, Kwangho LeeArchives of Pharmacal Research20142014https://doi.org/10.1007/s12272-013-0323-z
1816-Methoxyflavone Inhibits NFAT Translocation into the Nucleus and Suppresses T Cell ActivationJae-Seon So, Gi-Cheon Kim, Minkyung Song, Choong-Gu Lee, Eunbee Park, Ho Jin Kim, Young Sup Kim, Chang-Duk Jun and Sin-Hyeog ImThe Journal of Immunology2014, 193(6), 2772-27832014https://doi.org/10.4049/jimmunol.1400285
182Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitorsJimin Woo, Hyun-Young Kim, Byung Jin Byun, Chong-Hak Chae, Ji Young Lee, Shi Yong Ryu, Woo-Kyu Park, Heeyeong Cho, Gildon ChoiBioorganic & Medicinal Chemistry Letters2014, 24(11), 2486-24922014https://doi.org/10.1016/j.bmcl.2014.04.010
183Stereoselective synthesis of 4-substituted-cyclic sulfamidate-5-carboxylates by asymmetric transfer hydrogenation accompanied by dynamic kinetic resolution and applications to concise stereoselective syntheses of (-)-epi-cytoxazone and the taxotere side-chainJin-ah Kim, Yeon Ji Seo, Soyeong Kang, Juae Han and Hyeon-Kyu LeeChem. Commun.2014, 50, 13706-137092014https://doi.org/10.1039/C4CC06395C
184Coumarins reduce biofilm formation and the virulence ofEscherichia coli O157:H7Jin-Hyung Lee, Yong-Guy Kim, Hyun Seob Cho, Shi Yong Ryu, Moo Hwan Cho, Jintae LeePhytomedicine2014, 21, 1037-10422014https://doi.org/10.1016/j.phymed.2014.04.008
185Ginkgolic acids and Ginkgo biloba extract inhibit Escherichia coli O157:H7 and Staphylococcus aureus biofilm formationJin-Hyung Lee, Yong-Guy Kim, Shi Yong Ryu, Moo Hwan Cho, Jintae LeeInternational Journal of Food Microbiology2014, 174, 47-552014https://doi.org/10.1016/j.ijfoodmicro.2013.12.030
186Resveratrol Oligomers Inhibit Biofilm Formation of Escherichia coli O157:H7 and Pseudomonas aeruginosaJin-Hyung Lee, Yong-Guy Kim, Shi Yong Ryu, Moo Hwan Cho, Jintae LeeJournal of Natural Products2014, 77(1), 168-1722014https://doi.org/10.1021/np400756g
187Stilbenes Reduce Staphylococcus aureus Hemolysis, Biofilm Formation, and VirulenceLee Kayeon, Lee Jin-Hyung, Ryu Shi Yong, Cho Moo Hwan, and Lee JintaeFoodborne Pathogens and Disease2014, 11(9), 710-7172014https://doi.org/10.1089/fpd.2014.1758
188Dynamic Kinetic Resolution Based Asymmetric Transfer Hydrogenation of α.Alkoxy-β-Ketophosphonates. Diastereo- and Enantioselective Synthesis of Monoprotected 1,2-DihydroxyphosphonatesSe-Mi Son and Hyeon-Kyu LeeThe Journal of Organic Chemistry2014, 79, 2666-26812014https://doi.org/10.1021/jo500148j
189Discovery of substituted 6-pheny-3H-pyridazin-3-one derivatives as novel c-Met kinase inhibitorsSeung-Tae Kang, Eun-Young Kim, Raghavendra Archary, Heejung Jung, Chi Hoon Park, Chang-Soo Yun, Jong Yeon Hwang, Sang Un Choi, Chonghak Chae, Chong Ock Lee, Hyoung Rae Kim, Jae Du Ha, Dohyun Ryu, Sung Yun ChoBioorganic & Medicinal Chemistry Letters2014, 24, 5093-50972014https://doi.org/10.1016/j.bmcl.2014.08.067
190Synthesis and anti-influenza virus activity of 4-oxo- or thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-onesYe Jin Jang, Raghavendra Achary, Hye Won Lee, Hyo Jin Lee, Chong-Kyo Lee, Soo Bong Han, Young-Sik Jung, Nam Sook Kang, Pilho Kim, Meehyein KimAntiviral Research2014, 107, 66-752014https://doi.org/10.1016/j.antiviral.2014.04.013
191Xanthene Derivatives Increase Glucose Utilization through Activation of LKB1-Dependent AMP-Activated Protein KinaseYonghoon Kwon, Parkyong Song, Jong Hyuk Yoon, Jaewang Ghim, Dayea Kim, Byungjun Kang, Taehoon G. Lee, Jin-Ah Kim, Joong-Kwon Choi, In Kwon Youn, Hyeon-Kyu Lee, Sung Ho RyuPLOS One2014, 9(9), e1087712014https://doi.org/10.1371/journal.pone.0108771
192Novel bis-ortho-alkoxy-para-piperazinesubstituted-2, 4-dianilinopyrimidines (KRCA-0008) as potent and selective ALK inhibitors for anticancer treatmentChi Hoon Park, Hyeonjeong Choe, In-Young Jang, So Yeong Kwon, Muhammad Latif, Heung Kyoung Lee, Hyeon Ji Lee, Eun Hye Yang, Jeong In Yun, Chong Hak Chae, Sung Yun Cho, Sang Un Choi, Jae Du Ha, Heejung Jung, Hyoung Rae Kim, Pilho Kim, Chong Ock Lee, Chang-Soo Yun, Kwangho LeeBioorganic & Medicinal Chemistry Letters2013, 23(22), 6192-61962013https://doi.org/10.1016/j.bmcl.2013.08.090
193Elicitation of Induced Resistance against Pectobacterium carotovorum and Pseudomonas syringae by Specific Individual Compounds Derived from Native Korean Plant SpeciesGeun Cheol Song, Shi Yong Ryu, Young Sup Kim, Ji Young Lee, Jung Sup Choi and Choong-Min RyuMolecules2013, 18, 12877-128952013https://doi.org/10.3390/molecules181012877
194Identification of Novel Irreversible Inhibitors of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) from Haemophilus influenzaeHan SG, Lee WK, Jin BS, Lee KI, Lee HH, Yu YGJournal of Microbiology Biotechnology2013, 23(3), 329-3342013https://doi.org/10.4014/jmb.1210.10053
195Inhibition of Pseudomonas aeruginosa and Escherichia coli O157:H7 Biofilm Formation by Plant Metabolite ε-ViniferinHyun Seob Cho, Jin-Hyung Lee, Shi Yong Ryu, Sang Woo Joo, Moo Hwan Cho, and Jintae LeeJournal of Agricultural and Food Chemistry2013, 61(29), 7120-71262013https://doi.org/10.1021/jf4009313
196Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthaseJune-Haeng Cho, Mi-Young Lee, Irshad Ahmed Baig, Na-Reum Ha, Joungmok Kim, Moon-Young YoonBiochimie2013, 1-112013https://doi.org/10.1016/j.biochi.2013.03.007
197Discovery of Novel Scaffolds for Rho Kinase 2 Inhibitor Through TRFRET- Based High Throughput Screening AssayKwang-Seok Oh, Jihye Mun, Jae Eun Cho, Sunghou Lee, Kyu Yang Yi, Chae Jo Lim, Jin Soo Lee, Whui Jung Park and Byung Ho LeeCombinatorial Chemistry & High Throughput Screening2013, 16(1), 37-462013https://doi.org/10.2174/1386207311316010006
198Inhibition of influenza virus internalization by (-)-epigallocatechin-3-gallateMeehyein Kim, So-Yeon Kim, Hye Won Lee, Jin Soo Shin, Pilho Kim, Young-Sik Jung, Hyeong-Seop Jeong, Jae-Kyung Hyun, Chong-Kyo LeeAntiviral Research2013, 100, 460-4722013https://doi.org/10.1016/j.antiviral.2013.08.002
199New Natural Herbicide Candidate for Sicyon angulatus ControlNew Natural Herbicide Candidate for Sicyon angulatus ControlINTECH2013, chapter 122013https://doi.org/10.5772/54964
200Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitorsSung Yun Cho, Byung Ho Lee, Heejung Jung, Chang Soo Yun, Jae Du Ha, Hyoung Rae Kim, Chong Hak Chae, Jeong Hyun Lee, Ho Won Seo, Kwang-Seok OhJournal of Agricultural and Food Chemistry2013, 23(24), 6711-67162013https://doi.org/10.1016/j.bmcl.2013.10.036
201In silico identification of poly(ADP-ribose)polymerase-1 inhibitors and their chemosensitizing effects against cisplatin-resistant human gastric cancer cellsTuong Vy Thi Le, Jee Hee Suh, Nakjeong Kim, Hyun-Ju ParkBioorganic & Medicinal Chemistry Letters2013, 23(9), 2642-26462013https://doi.org/10.1016/j.bmcl.2013.02.094
202Efficient synthesis of 3H,3'H-spiro[benzofuran-2,1'-isobenzofuran]-3,3'-dione as novel skeletons specifically for influenza virus type B inhibitionYashwardhan Malpani, Raghavendra Achary, So Yeon Kim, Hee Chun Jeong, Pilho Kim, Soo Bong Han, Meehyein Kim,, Chong-Kyo Lee, Jae Nyoung Kim, Young-Sik JungEuropean Journal of Medicinal Chemistry2013, 62, 534-5442013https://doi.org/10.1016/j.ejmech.2013.01.015
203Characterization of DDRI-18 (3,3′-(1H,3′H-5,5′-bibenzo[d]imidazole-2,2′-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage responseDW Jun, YS Jeong, HJ Kim, K-C Jeong, S Kim, C-H LeeBritish Journal of Pharmacology2012, 167(1), 141-1502012https://doi.org/10.1111/j.1476-5381.2012.01977.x
204Proteolytic assay-based screening identifies a potent inhibitor of anthrax lethal factorHae-Chul Park, So-Ra Sung, Su Min Lim, Jong-Sun Lee, Sung-Kun Kim, Moon-Young YoonMicrobial Pathogenesis2012, 53, 109-1122012https://doi.org/10.1016/j.micpath.2012.04.004
205Identification and characterization of triamcinolone acetonide, a microglial-activation inhibitorJinpyo Hong, Bo-Kyong Kim, Hyoungsub Lim, Soojin Lee, Sung Joong LeeImmunopharmacology and Immunotoxicology2012, 34(6), 912-9182012https://doi.org/10.3109/08923973.2012.671332
206Plumbagin as a new natural herbicide candidate for Sicyon angulatus control agent with the target 8-amino-7-oxononanoate synthaseJung-Sup Choi, No-Joong Park, Hee-Kyung Lim, Young-Kwan Ko, Young-Sup Kim, Shi-Yong Ryu, In-Taek HwangPesticide Biochemistry and Physiology2012, 103, 166-1722012https://doi.org/10.1016/j.pestbp.2012.04.007
207Inhibitory Effect of 4-Aryl 2-Substituted Aniline-thiazole Analogs on Growth of Human Prostate Cancer LNCap CellsSeung-hwa Baek, Nakjeong Kim, Seong Hwan Kim, Kwang Hwa Park, Kyung-Chae Jeong, Bae Keun Park and Nam Sook KangBulletin of the Korean Chemical Society2012, 33(1), 111-1142012https://doi.org/10.5012/bkcs.2012.33.1.111
208A compound(DW1182v) protecting high glucose/palmitate-induced glucolipotoxicity to INS-1 beta cells preserves islet integrity and improves hyperglycemia in obese db/db mouseSoo-Jin Lee, Sung-E Choi, Yun Cheong Hwang, Ik-Rak Jung, Sang-A Yi, Jong Gab Jung, Jin-Mo Ku, Kwiwan Jeoung, Seung Jin Han, Hae Jin Kim, Dae Jung Kim, Kwan-Woo Lee, Yup KangEuropean Journal of Pharmacology2012, 696(1-3), 187-1932012https://doi.org/10.1016/j.ejphar.2012.09.023
209Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitisSuk-Kyeong Jung, Youngkyung Ko, Keum Ran Yu, Ju Hee Kim, Joo-Youn Lee, Chong Hak Chae, Suk Ji, Chang Hyen Kim, Hyeon Kyu Lee, Eun Bok Choi, Bo Yeon Kim, Raymond L. Erikson, Sang J. Chung, Seung Jun KimBioorganic and Medicinal Chemistry Letters2012, 22(5), 2084-20882012https://doi.org/10.1016/j.bmcl.2012.01.011
210Identification of novel mPGES-1 inhibitors through screening of a chemical librarySung-Jun Park, Seong-Gu Han, Hafiz Muhammad Ahsan, Kijae Lee, Jae Yeol Lee, Ji-Sun Shin, Kyung-Tae Lee, Nam-Suk Kang, Yeon Gyu YuBioorganic & Medicinal Chemistry Letters2012, 22, 7335-73392012https://doi.org/10.1016/j.bmcl.2012.10.085
211Protein Tyrosine Phosphatase 1B Inhibitors: A Molecular Level Legitimate Approach for the Management of Diabetes MellitusSuresh Thareja, Saurabh Aggarwal, T. R. Bhardwaj, Manoj KumarMedicinal Research Reviews2012, 32(3), 459-5172012https://doi.org/10.1002/med.20219
212Structure-Activity Relationships and Optimization of 3,5-Dichloropyridine Derivatives As Novel P2X7 Receptor AntagonistsWon-Gil Lee, So-Deok Lee, Joong-Heui Cho, Younghwan Jung, Jeong-hyun Kim, Tran T. Hien, Keon-Wook Kang, Hyojin Ko, and Yong-Chul KimJournal of Medicinal Chemistry2012, 55, 3687-36982012https://doi.org/10.1021/jm2012326
213An In Vivo C. elegans Model System for Screening EGFR-Inhibiting Anti-Cancer DrugsYoung-Ki Bae, Jee Young Sung, Yong-Nyun Kim, Sunshin Kim, Kyeong Man Hong, Heung Tae Kim, Min Sung Choi, Jae Young Kwon, Jaegal ShimPLoS ONE2012, 7(9), e424412012https://doi.org/10.1371/journal.pone.0042441
214Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancerAkira Ooki, Keishi Yamashita, Shiro Kikuchi, Shinichi Sakuramoto, Natsuya Katada, Mina Waraya, Hiroshi Kawamata, Hiroshi Nishimiya, Kazunori Nakamura and Masahiko WatanabeBMC Cancer2011, 11, 1222011https://doi.org/10.1186/1471-2407-11-122
215High-Throughput Methods in Identification of Protein Tyrosine Phosphatase Inhibitors and ActivatorsElina Mattila and Johanna IvaskaAnti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Cancer Agents)2011, 11(1), 141-1502011https://doi.org/10.2174/187152011794941235
216Chemical compound 31002 stimulates cardiomyogenic differentiation of embryonic stem cellsEun Kyoung Kim, Mi-Young Son, Youngkuk Kang, Chang-Hee Lee, Hae Rim Kim, Youngsuk Won, Wonkee Yoon, Hyoung-Chin Kim, and Ki-Hoan NamLab Anim Res2011, 27(3), 205-2122011https://doi.org/10.5625/lar.2011.27.3.205
217Development and Comparison of Whole-Cell Assay Systems for Quorum-Sensing Inhibitors Based on TraR, LasR, and QscRHai-Bo Liu, Jung Sun Kim and Sunghoon ParkJournal of Biomolecular Screening2011, 16(9), 986-9942011https://doi.org/10.1177/1087057111416656
218Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discoveryHyun Uk Kim, Soo Young Kim, Haeyoung Jeong, Tae Yong Kim, Jae Jong Kim, Hyon E Choy, Kyu Yang Yi, Joon Haeng Rhee, Sang Yup LeeMolecular Systems Biology2011, 460, 1-152011https://doi.org/10.1038/msb.2010.115
219Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imagingJae Hong Lee, Ju-Hoon So, Jong Hyun Jeon, Eun Bok Choi, Yu-Ri Lee, Young-Tae Chang, Cheol-Hee Kim, Myung Ae Bae and Jin Hee AhnChemical Communications2011, 47(26), 7500-75022011https://doi.org/10.1039/C1CC11253H
220Selective Killing of Bacterial Persisters by a Single Chemical Compound without Affecting Normal Antibiotic-Sensitive CellsJun-Seob Kim, Paul Heo, Tae-Jun Yang, Ki-Sing Lee, Da-Hyeong Cho, Bum Tae Kim, Ji-Hee Suh, Hee-Jong Lim, Dongwoo Shin, Sung-Koo Kim, and Dae-Hyuk KweonANTIMICROBIAL AGENTS AND CHEMOTHERAPY2011, 55(11), 5380-53832011https://doi.org/10.1128/AAC.00708-11
2214-Chlorotetrazolo[1,5-a]quinoxaline inhibits activation of Syk kinase to suppress mast cells in vitro and mast cell-mediated passive cutaneous anaphylaxis in miceKui Lea Park, Na Young Ko, Jun Ho Lee, Do Kyun Kim, Hyuk Soon Kim, A-Ram Kim, Erk Her, Bokyung Kim, Hyung Sik Kim, Eun-Yi Moon, Young Mi Kim, Hang-Rae Kim, Wahn Soo ChoiToxicology and Applied Pharmacology2011, 257, 235-2412011https://doi.org/10.1016/j.taap.2011.09.009
222Novel PPARgamma partial agonists with weak activity and no cytotoxicity; identified by a simple PPARgamma ligand screening systemMin-Chul Cho, Dong-Hun Lee, Eun Jin Kim, Jee-young Lee, Jeong-Woo Kang, Jong Hwan Song, Youhoon Chong, Yangmi Kim, Jin-Tae Hong, Do-Young YoonMolecular and Cellular Biochemistry2011, 358, 75-832011https://doi.org/10.1007/s11010-011-0923-1
223Development of a High-Content Screening Method for Chemicals Modulating DNA Damage ResponseSunshin Kim, Dong Hwa Jun, Hye Jin Kim, Kyung-Chae Jeong, Chang-Hun LeeJournal of Biomolecular Screening2011, 16(2), 259-2652011https://doi.org/10.1177/1087057110392993
224KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to the hsp70 PromoterYoung Ju Yoon, Joo Ae Kim, Ki Deok Shin, Dae-Seop Shin, Young Min Han, Yu Jin Lee, Jin Soo Lee, Byoung-Mog Kwon, and Dong Cho HanThe Journal of Biological Chemistry2011, 286(3), 1737-17472011https://doi.org/10.1074/jbc.M110.179440
225Inhibitors of the Pseudomonas aeruginosa quorum-sensing regulator, QscRHai-Bo Liu, Joon-Hee Lee, Jung Sun Kim and Sunghoon ParkBiotechnology and Bioengineering2010, 106(1), 119-1262010https://doi.org/10.1002/bit.22672
226Autophagonizer, a novel synthetic small molecule, induces autophagic cell deathIn-Kwon Choi, Yoon Sun Cho, Hye Jin Jung, Ho Jeong KwonBiochemical and Biophysical Research Communications2010, 393, 849-8542010https://doi.org/10.1016/j.bbrc.2010.02.097
227Anti-inflammatory effects of synthetic compound KT-14480 in lipopolysaccharide-stimulated microglia cellsJiyeon Ock, Kyoungho SukJournal of Pharmacy and Pharmacology2010, 62(2), 279-2852010https://doi.org/10.1211/jpp.62.02.0017
228A novel anti-neuroinflammatory pyridylimidazole compound KR-31360Jiyeon Ock, Sangseop Kim, Kyu-Yang Yi, Nak-Jung Kim, Hyung Soo Han, Je-Yoel Cho, Kyoungho SukBiochemical Pharmacology2010, 79, 596-6092010https://doi.org/10.1016/j.bcp.2009.09.026
229Identification of KT-15073 as an Inhibitor of Lipopolysaccharide-Induced Microglial ActivationJiyeon Ock, Su Hyung Hong, Kyoungho SukBiological and Pharmaceutical Bulletin2010, 33(3), 461-4672010https://doi.org/10.1248/bpb.33.461
230Identification of an ABCB/P-glycoprotein-specific Inhibitor of Auxin Transport by Chemical GenomicsJun-Young Kim, Sina Henrichs, Aurelien Bailly, Vincent Vincenzetti, Valpuri Sovero, Stefano Mancuso, Stephan Pollmann, Daehwang Kim, Markus Geisler,and Hong-Gil NamThe Journal of Biological Chemistry2010, 285(30), 23309-233172010https://doi.org/10.1074/jbc.M110.105981
231Identification of gp96 as a Novel Target for Treatment of Autoimmune Disease in MiceJung Min Han, Nam Hoon Kwon, Jin Young Lee, Seung Jae Jeong, Hee Jung Jung, Hyeong Rae Kim, Zihai Li, Sunghoon KimPLoS ONE2010, 5(3), e97922010https://doi.org/10.1371/journal.pone.0009792
232Identification of Novel Scaffolds for IkB Kinase Beta Inhibitor via a High Throughput Screening TR-FRET AssayKwang-Seok Oh, Sunghou Lee, Joong Kwon Choi and Byung Ho LeeCombinatorial Chemistry & High Throughput Screening2010, 13, 790-7972010https://doi.org/10.2174/138620710792927367
233Small-molecule inhibitors of c-Myc transcriptional factor suppress proliferation and induce apoptosis of promyelocytic leukemia cell via cell cycle arrestKyung-Chae Jeong,Kyung-Ohk Ahn and Chul-Hak YangMolecular BioSystems2010, 6(8), 1503-15092010https://doi.org/10.1039/c002534h
234Characterization of Acetohydroxyacid Synthesis I from Escherichia coli K-12 and Identification of Its InhibitorsPham Ngoc Chien, Ji-Young Moon, Jun-Haeng Cho, Soo-Jae Lee, Joon-Shik Park, Dong-Eun Kim, Yoonkyung Park, and Moon-Young YoonBiosci. Biotechnol. Biochem2010, 74(11), 2281-22862010https://chembank.org/%ed%99%9c%ec%9a%a9%eb%85%bc%eb%ac%b8/%E2%80%A2%20https://doi.org/10.1271/bbb.100496
235Discovery of cyclicsulfonamide derivatives as 11b-hydroxysteroid dehydrogenase 1 inhibitorsSe Hoan Kim, Ravirala Ramu, Sung Wook Kwon, Su-Hee Lee, Chi Hyun Kim, Seung Kyu Kang, Sang Dal Rhee, Myung Ae Bae, Sung Hoon Ahn, Duck Chan Ha, Hyae Gyeong Cheon, Ki Young Kim, Jin Hee AhnBioorganic & Medicinal Chemistry Letters2010, 20, 1065-10692010https://doi.org/10.1016/j.bmcl.2009.12.035
236Individual and common inhibitors of coronavirus and picornavirus main proteasesChih-Jung Kuo, Hun-Ge Liu, Yueh-Kuei Lo, Churl-Min Seong, Kee-In Lee, Young-Sik Jung, Po-Huang LiangFEBS Letters2009, 583, 549-5552009https://doi.org/10.1016/j.febslet.2008.12.059
237Identification of 3-acetyl-2-aminoquinolin-4-one as a novel, nonpeptidic scaffold for specific calpain inhibitory activityDa-Hye Kang, Kyu-Yeon Jun, Jin Pyo Lee, Chwang Siek Pak, Younghwa Na, and Youngjoo KwonJournal of Medicinal Chemistry2009, 52(9), 3093-30972009https://doi.org/10.1021/jm8014734
238Synthesis and structure?activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonistsGa Eun Lee, Ho-Sung Lee, So Deok Lee, Jung-Ho Kim, Won-Ki Kim, Yong-Chul KimBioorganic & Medicinal Chemistry Letters2009, 19, 954-9582009https://doi.org/10.1016/j.bmcl.2008.11.088
239Purinergic P2X7 receptor antagonists: Chemistry and fundamentals of biological screeningHendra Gunosewoyo, Mark J. Coster, Maxwell R. Bennett, Michael KassiouBioorganic & Medicinal Chemistry2009, 17, 4861-48652009https://doi.org/10.1016/j.bmc.2009.05.083
240Modulation of Osteocalcin Expression by Purmorphamine DerivativesHye-Ryun Kim, So-Hee Jeong, Young-Sam Im, Sung Yun Cho, Joong-Kwon Choi, Hea Kyeong Shin, Yong-Min Kim, Jin-Ook Song, Seong-Ho Jeon and Joong-Kook ChoiGENES & GENOMICS2009, 31(3), 261-2662009https://doi.org/10.1007/BF03191198
241Anti-inflammatory effects of a fluorovinyloxyacetamide compound KT-15087 in microglia cellsJiyeon Ock, Sangseop Kim, Kyoungho SukPharmacological Research2009, 59(6), 414-4222009https://doi.org/10.1016/j.phrs.2009.02.008
242Induction of neurogenesis in rat bone marrow mesenchymal stem cells using purine structure-based compoundsMi Hee Cho, Jung Hwa Lee, Hyun Hee Ahn, Ju Young Lee, E Sle Kim, Yun Mi Kang, Byoung Hyun Min, Jae Ho Kim, Hai Bang Lee and Moon Suk KimMolecular BioSystems2009, 5, 609-6112009https://doi.org/10.1039/B905598N
243Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-α mRNAMin-Ju Chae, Hye Youn Sung, Eun-Hye Kim, Mira Lee, Hojoong Kwak, Chong Hak Chae, Sunwoo Kim and Woong-Yang ParkEXPERIMENTAL and MOLECULAR MEDICINE2009, 41(11), 824-8312009https://doi.org/10.3858/emm.2009.41.11.088
244Identification of Osteogenic Purmorphamine DerivativesSung-Jin Lee; Hak-Kyo Lee; Sung Yun Cho; Joong-Kwon Choi; Hea Kyeong Shin; Eun-Jung Kwak; Mi-Ran Cho; Hye-Ryun Kim; Seung-Ryol Kim; Yong-Min Kim; Kyoung-Jin Park; Joong-Kook ChoiMolecules & Cells2008, 26(4), 380-3862008http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&i=0578320080260040380&m=VIEW
245Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitorsKyoung-Jae Choi, Kyoung Mi Noh, Dong-Eun Kim, Byung Hak Ha, Eunice Eunkyung Kim, Moon-Young YoonArchives of Biochemistry and Biophysics2007, 466, 24-302007https://doi.org/10.1016/j.abb.2007.07.011
246What's new on CDC25 phosphatase inhibitorsMarie-Odile Contour-Galcera, Alban Sidhu, Gregoire Prevost, Dennis Bigg, Bernard DucommunPharmacology & Therapeutics2007, 115, 1-122007https://doi.org/10.1016/j.pharmthera.2007.03.009
247[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigsYong Joo Na, Heung Su Baek, Soo Mi Ahn, Hyun Jung Shin, Ih-Seop Chang, Jae Sung HwangBiochemical Pharmacology2007, 74, 780-7862007https://doi.org/10.1016/j.bcp.2007.05.028
248Indenone Derivatives: A Novel Template for Peroxisome Proliferator-Activated Receptor γ (PPARγ) AgonistsJin Hee Ahn, Mi Sik Shin, Sun Ho Jung, Seung Kyu Kang, Kwang Rok Kim, Sang Dal Rhee, Won Hoon Jung, Sung Don Yang, Seung Jun Kim, Joo Rang Woo, Jeong Hyung Lee, Hyae Gyeong Cheon and Sung Soo KimJournal of Medicinal Chemistry2006, 49, 4781-47842006https://doi.org/10.1021/jm060389m
249Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitorsJin Hee Ahn, Seung Jun Kim, Woul Seong Park, Sung Yun Cho, Jae Du Ha, Sung Soo Kim, Seung Kyu Kang, Dae Gwin Jeong, Suk-Kyeong Jung, Sang-Hyeup Lee, Hwan Mook Kim, Song Kyu Park, Ki Ho Lee, Chang Woo Lee, Seong Eon Ryu and Joong-Kwon ChoiBioorganic & Medicinal Chemistry Letters2006, 16, 2996-29992006https://doi.org/10.1016/j.bmcl.2006.02.060
250Synthesis and biological evaluation of 5-arylamino-6-chloro-1H-indazole-4,7-diones as inhibitors of protein kinase B/AktJong Hee Ko, Seung Woo Yeon, Jung Su Ryu, Tae-Yong Kim, Eun-Ha Song, Hea-Jung You, Rae-Eun Park and Chung-Kyu RyuBioorganic & Medicinal Chemistry Letters2006, 16, 6001-60052006https://doi.org/10.1016/j.bmcl.2006.08.120
251PTP-1B inhibitors: Cyclopenta[d][1,2]-oxazine derivativesSung Yun Cho, Ji Yoen Baek, Sang Sub Han, Seung Kyu Kang, Jae Du Ha, Jin Hee Ahn, Jae Don Lee, Kwang Rok Kim, Hyae Gyeong Cheon, Sang Dal Rhee, Sung Don Yang, Gyu Hwan Yon, Chwang Siek Pak and Joong-Kwon ChoiBioorganic & Medicinal Chemistry Letters2006, 16, 499-5022006https://doi.org/10.1016/j.bmcl.2005.10.062
252Development of a time-resolved fluorometric assay for the high throughput screening of melanin concentrating hormone receptor antagonistsSunghou Lee, Gun-Do Kim, Woo-Kyu Park, Heeyeong Cho, Byung Ho Lee, Sung-eun Yoo, Jae Yang KongJournal of Pharmacological and Toxicological Methods2006, 53, 242-2472006https://doi.org/10.1016/j.vascn.2005.09.001
253Inhibition of dipeptidyl peptidase IV by novel inhibitors with pyrazolidine scaffoldHyae Gyeong Cheon, Sung-Soo Kim, Kwang-Rok Kim, Sang-Dal Rhee, Sung-Don Yang, Jin Hee Ahn, Sung-Dae Park, Jae Mok Lee, Won Hoon Jung, Hye Sook Lee, Hee Youn KimBiochemical Pharmacology2005, 70, 22-292005https://doi.org/10.1016/j.bcp.2005.04.004
254Synthesis and evaluation of pyrazolidine derivatives as dipeptidyl peptidase IV (DP-IV) inhibitorsJin Hee Ahn, Jin Ah Kim, Hye-Min Kim, Hyuk-Man Kwon, Sun-Chul Huh, Sang Dal Rhee, Kwang Rok Kim, Sung-Don Yang, Sung-Dae Park ,Jae Mok Lee, Sung Soo Kim and Hyae Gyeong CheonBioorganic & Medicinal Chemistry Letters2005, 15, 1337-13402005https://doi.org/10.1016/j.bmcl.2005.01.020
255Pyrazolidine Derivatives with Heteroaryl Urea as Dipeptidyl Peptidase IV InhibitorsJin Hee AHN, Sun Ho JUNG, Jin Ah KIM, Seog Beom SONG, Soon Ji KWON, Kwang Rok KIM, Sang Dal RHEE, Sung-Dae PARK, Jae Mok LEE, Sung Soo KIM, and Hyae Gyeong CHEONChem. Pharm. Bull2005, 53(8), 1048-10502005https://doi.org/10.1248/cpb.53.1048
256Blocking Tumor Cell Migration and Invasion with Biphenyl Isoxazole Derivative KRIBB3, a Synthetic Molecule That Inhibits Hsp27 PhosphorylationKi Deok Shin, Mi-Young Lee, Dae-Seop Shin, Sangku Lee, Kwang-Hee Son, Sukhoon Koh, Young-Ki Paik, Byoung-Mog Kwon, and Dong Cho HanThe Journal of Biological Chemistry2005, 280(50), 41439-414482005https://doi.org/10.1074/jbc.M507209200
257EK-6136 (3-methyl-4-(O-methyl-oximino)-1-phenylpyrazolin-5-one): A novel Cdc25B inhibitor with antiproliferative activityKim, Kwang-Rok; Kwon, Ju-Lee; Kim, Ji-Sun; No, Zaesung; Kim, Hyoung Rae; Cheon, Hyae GyeongEuropean Journal of Pharmacology2005, 528(1-3), 37-422005https://doi.org/10.1016/j.ejphar.2005.10.027
258EK-6136 (3-methyl-4-(O-methyl-oximino)-1-phenylpyrazolin-5-one): A novel Cdc25B inhibitor with antiproliferative activityKwang-Rok Kim, Ju-Lee Kwon, Ji-Sun Kim, Zaesung No, Hyoung Rae Kim, Hyae Gyeong CheonEuropean Journal of Pharmacology2005, 528, 37-422005https://doi.org/10.1016/j.ejphar.2005.10.027
259KR-62436, 6-{2-[2-(5-cyano-4,5-dihydropyrazol-1-yl)-2-oxoethylamino]ethylamino}nicotinonitrile, is a novel dipeptidyl peptidase-IV (DPP-IV) inhibitor with anti-hyperglycemic activityKwang-Rok Kim, Sang-Dal Rhee, Hee Youn Kim, Won Hoon Jung, Sung-Don Yang, Sung Soo Kim, Jin Hee Ahn, Hyae Gyeong CheonEuropean Journal of Pharmacology2005, 518, 63-702005https://doi.org/10.1016/j.ejphar.2005.05.030
260(E)-Phenyl- and -heteroaryl-substituted O-benzoyl- (or acyl)oximes as lipoprotein-associated phospholipase A2 inhibitorsTae-Sook Jeong, Mi Jeong Kim, Hana Yu, Kyung Soon Kim, Joong-Kwon Choi, Sung-Soo Kim and Woo Song LeeBioorganic & Medicinal Chemistry Letters2005, 15, 1525-15272005https://doi.org/10.1016/j.bmcl.2004.11.063
261Position of Pro and Ser near Glu7.32 in the Extracellular Loop 3 of Mammalian and Nonmammalian Gonadotropin-Releasing Hormone (GnRH) Receptors Is a Critical Determinant for Differential Ligand Selectivity for Mammalian GnRH and Chicken GnRH-IICHENGBING WANG, OIM YUN, KAUSHIK MAITI, DA YOUNG OH, KYEONG KYU KIM, CHONG HAK CHAE, CHANG JUN LEE, JAE YOUNG SEONG, AND HYUK BANG KWONMolecular Endocrinology2004, 18(1), 105-1162004https://doi.org/10.1210/me.2003-0101
262Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agentCheon, Hyae Gyeong; Kim, Sun-Mee; Yang, Sung-Don; Ha, Jae Du; Choi, Joong-KwonEuropean Journal of Pharmacology2004, 485(1-3), 333-3402004https://doi.org/10.1016/j.ejphar.2003.11.070
263Discovery of a novel protein tyrosine phosphatase-1B inhibitor, KR61639: potential development as an antihyperglycemic agentHyae Gyeong Cheon, Sun-Mee Kim, Sung-Don Yang, Jae Du Ha, Joong-Kwon ChoiEuropean Journal of Pharmacology2004, 485, 333- 3392004https://doi.org/10.1016/j.ejphar.2003.11.070
264Lead discovery of quinoxalinediones as an inhibitor of dipeptidyl peptidase-IV (DPP-IV) by high-throughput screeningHyae-Gyeong Cheon, Chul-Min Lee, Beom-Tae Kim and Ki-Jun HwangBioorganic & Medicinal Chemistry Letters2004, 14, 2661-26642004https://doi.org/10.1016/j.bmcl.2004.02.065
265Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agentsJin Hee Ahn, Hye-Min Kim, Sun Ho Jung, Seung Kyu Kang, Kwang Rok Kim, Sang Dal Rhee, Sung-Don Yang, Hyae Gyeong Cheon and Sung Soo KimBioorganic & Medicinal Chemistry Letters2004, 14, 4461-44652004https://doi.org/10.1016/j.bmcl.2004.06.046
266Protein Tyrosine Phosphatase 1B Inhibitors: CatecholsJin Hee Ahn, Sung Yun Cho, Jae Du Ha, Seung Kyu Kang, Sun Ho Jung, Hye-Min Kim, Sung Soo Kim, Kwang Rok Kim, Hyae Gyeong Cheon, Sung-Don Yang, and Joong-Kwon ChoiBulletin of the Korean Chemical Society2003, 24(10), 1505-15082003https://doi.org/10.5012/bkcs.2003.24.10.1505
267Protein Tyrosine Phosphatase 1B Inhibitors: Heterocyclic Carboxylic AcidsSung Yun Cho, Jin Hee Ahn, Jae Du Ha, Seung Kyu Kang, Ji Yoen Baek, Sang Sub Han, Eun Young Shin, Sung Soo Kim, Kwang Rok Kim, Hyae Gyeong Cheon, and Joong-Kwon ChoiBulletin of the Korean Chemical Society2003, 24(10), 1455-14642003https://doi.org/10.5012/bkcs.2003.24.10.1455
268Design, Syntheses and Biological Evaluations of Nonpeptidic Caspase 3 InhibitorsEun-sook Kim, Sung-eun Yoo, Kyu Yang Yi, Sunkyung Lee, Jae-sung Noh, Yong-Sam Jung, Eunhee Kim, and Nakcheol JeongBulletin of the Korean Chemical Society2002, 23(7), 1003-11102002https://doi.org/10.5012/bkcs.2002.23.7.1003
269Synthesis and PTP1B Inhibition of 1,2-Naphthoquinone Derivatives as Potent Anti-Diabetic AgentsJin Hee Ahn,y Sung Yun Cho,y Jae Du Ha,y So Young Chu, Sun Ho Jung, Yoon Sung Jung, Ji Yoen Baek, In Kyung Choi, Eun Young Shin, Seung Kyu Kang, Sung Soo Kim, Hyae Gyeong Cheon, Sung-Don Yang and Joong-Kwon ChoiBioorganic & Medicinal Chemistry Letters2002, 12, 1941-19462002https://doi.org/10.1016/S0960-894X(02)00331-1