연구동향
Benzothiazole scaffold as novel HCV inhibitor
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Date
2016-01-29 09:47
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7814
The discovery and characterization of a novel scaffold as a potent hepatitis C virus inhibitor
(출처) Chemical Communications, 2016, ASAP. DOI: 10.1039/c5cc10594c
A novel anti-HCV benzothiazole scaffold was discovered by phenotypic screening of in house chemical library.
Further target characterization and structural optimization studies revealed that the benzothiazole-disulfoamide derivatives were potent anti-HCV molecules with good selectivity and acted by targeting NS5A.?
DOI: 10.1039/c5cc10594c
링크:http://pubs.rsc.org/en/content/articlelanding/2016/cc/c5cc10594c
(출처) Chemical Communications, 2016, ASAP. DOI: 10.1039/c5cc10594c
A novel anti-HCV benzothiazole scaffold was discovered by phenotypic screening of in house chemical library.
Further target characterization and structural optimization studies revealed that the benzothiazole-disulfoamide derivatives were potent anti-HCV molecules with good selectivity and acted by targeting NS5A.?
DOI: 10.1039/c5cc10594c
링크:http://pubs.rsc.org/en/content/articlelanding/2016/cc/c5cc10594c